The cells’ altered proliferation rates hint at ways to diagnose and potentially treat autism earlier.
Spectrum: Autism Research News
Tag: brain size
The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.
The size of the cerebral cortex seems to depend on when neural progenitor cells multiply or differentiate into glial cells and neurons.
Some genomic areas that help determine cerebellar size are associated with autism, schizophrenia and bipolar disorder, according to a new study. But heritable variants across the genome that also influence cerebellar size are not.
The X chromosome holds stronger-than-expected genetic sway over the structure of several brain regions. The genes that may underlie this oversized influence have ties to autism.
Inhibiting a protein that helps cells move or change shape prevents atypical neuronal migration in 3D clusters of brain cells carrying autism-linked genetic variants.
When Holly Stessman isn’t probing autism genes, she is tending to her flock of chickens or seeking out the next great sci-fi movie.
An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.