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Spectrum: Autism Research News

Tag: brain size

June 2022

Different forms of autism have opposite problems with brain precursor cells

by  /  10 June 2022

The cells’ altered proliferation rates hint at ways to diagnose and potentially treat autism earlier.

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May 2022
Three views of zebrafish.

Novel gene linked to brain size in autistic people

by  /  16 May 2022

The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.

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Organoids hint at origins of enlarged brains in autistic people

by  /  13 May 2022

The size of the cerebral cortex seems to depend on when neural progenitor cells multiply or differentiate into glial cells and neurons.

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MRIs

Growth charts map brain changes across lifespan

by  /  12 May 2022

The new resource is the first to chart human brain development from before birth to 100 years of age.

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February 2022

Cerebellum size shows tenuous genetic link to autism

by  /  21 February 2022

Some genomic areas that help determine cerebellar size are associated with autism, schizophrenia and bipolar disorder, according to a new study. But heritable variants across the genome that also influence cerebellar size are not.

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September 2021
Four brains showing areas affected by the X chomosome in yellow

X chromosome exerts extra influence on brain development

by  /  15 September 2021

The X chromosome holds stronger-than-expected genetic sway over the structure of several brain regions. The genes that may underlie this oversized influence have ties to autism.

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Colorful illustration shows a esearcher with frogs and frog eggs.

Autism research makes the leap to frogs

by  /  8 September 2021

Frogs are useful for autism research for a slew of reasons, including the fact that the animals’ initial development occurs outside of the mother’s body in plain view.

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neurons in organoids

Protein inhibitor normalizes neuronal migration in organoid model of autism

by  /  1 September 2021

Inhibiting a protein that helps cells move or change shape prevents atypical neuronal migration in 3D clusters of brain cells carrying autism-linked genetic variants.

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August 2021
Holly Stessman standing in her garden looking up and holding her two chickens.

Beyond the Bench: A conversation with Holly Stessman

by  /  13 August 2021

When Holly Stessman isn’t probing autism genes, she is tending to her flock of chickens or seeking out the next great sci-fi movie.

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May 2021
Microglia activity seen in red, green and blue.

Autism mutation may cause big brain via ‘don’t eat me’ signals

by  /  17 May 2021

An autism-linked mutation could make the brain grow unusually large by prompting cells to express a chemical signal better known for its connection to cancer.

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