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Society for Neuroscience 2019

SFN 2019
Coloured transmission electron micrograph (TEM) showing several unmyelinated (green) and myelinated (green with blue border) axons. Schwann cell cytoplasm is red and a nucleus (bottom left) is yellow. The pink lines are the basement membranes.

Loss of insulation on neurons may contribute to autism

by  /  6 March 2020
Genes involved in the formation of myelin, a fatty substance that sheathes neurons, are altered in autistic people and in several mouse models.
SFN 2019

In brain imaging studies of autism, location may alter results

by  /  27 January 2020
A new analysis hints at the source of the rampant inconsistency among brain imaging studies in autism: significant differences among study sites.
SFN 2019
Micrograph of brain organoid in green and red

Spheres of brain cells may offer crystal ball for autism’s origins

by  /  24 January 2020
Researchers have monitored the active genome in brain organoids over the course of nearly two years — and may find clues to autism’s roots.
October 2019
DNA
SFN 2019

Rapid assay flags autism mutations in regions that flank genes

by  /  21 October 2019

Researchers have identified mutations within regulatory regions that are likely to contribute to autism, using a speedy system of DNA ‘barcodes.’

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Two mice in a lab test environment
SFN 2019

Single seizure may have long-lasting effects on brain

by  /  21 October 2019

A single seizure early in life leads to enduring behavioral problems, including diminished sociability, in mice.

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SFN 2019

Mock flu triggers changes in brain, behavior of monkeys

by  /  20 October 2019

Marmosets exposed to a mock infection in the womb have altered vocal development and diminished social interest; exposed macaques show changes in brain structure and function.

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SFN 2019

Unusual gait marks mice with mutations related to autism

by  /  20 October 2019

Mouse models of two genetic conditions related to autism show abnormalities in their movement patterns.

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SFN 2019

Algorithm may help identify subgroups of autism

by  /  20 October 2019

A new algorithm accurately separates highly similar people into subgroups based on their brain activity — and could do the same for autistic people.

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SFN 2019

Breaks in long genes may underpin some forms of autism

by  /  20 October 2019

Neurons derived from autistic people with enlarged brains show extensive damage to long genes.

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SFN 2019

CRISPR therapy may reverse autism mutation’s effects well past infancy

by  /  20 October 2019

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

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SFN 2019

Looking directly in the eyes engages region of the social brain

by  /  20 October 2019

The social brain has a sweet spot that activates when people look each other in the eyes but not when they look at eyes in a video.

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SFN 2019

Most people underestimate risk of others’ access to their biological data

by  /  20 October 2019

People in the United States view certain personal information, such as their social security number, as more sensitive than data about their physical or mental well-being.

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Grid of views of mouse brain: 3D and areas mapped in color
SFN 2019

New mouse brain atlas merges two popular maps

by  /  20 October 2019

A new online resource aligns and improves the two most widely used mouse brain atlases.

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