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Spectrum: Autism Research News

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Signs & Symptoms

Autism’s core symptoms accompany a constellation of subtle signs that scientists are just beginning to unmask.

February 2011

New diagnostic criteria for autism fuel debate

by  /  28 February 2011

The new edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM) won’t be published for another two years, but changes proposed to the diagnostic criteria for autism are already sparking heated debate.

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Painting a picture

by  /  25 February 2011

A new technique documents real-time action in neurons by harnessing the changes in light that take place when they fire.

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Genetics: Study reexamines role of 16p11.2 in autism

by  /  23 February 2011

Duplication or deletion of 16p11.2 — a much-studied chromosomal region with a strong association with autism — is present in 0.76 percent of people with the disorder, according to a meta-analysis published February in Genetics in Medicine.

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Database organizes multiple mouse models

by  /  23 February 2011

A genetic database of autism genes, called Autism Database, or AutDB, details curated information for more than 200 mouse models of autism, according to a report in the January BMC Genomics.

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Bad trip

by  /  22 February 2011

Hallucinogens like LSD and MDMA may help people with autism become more sociable, but negative side effects argue against their use.

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Cognition and behavior: Serotonin pathway affects mouse behavior

by  /  22 February 2011

Mice that lack the gene for integrin β3, or ITGB3 — which regulates the levels of serotonin in the blood — groom themselves frequently and show less interest in stranger mice compared with controls, according to a study published in February in Autism Research as part of a special issue on mouse models in autism.

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Genetic background alters behavior of fragile X mice

by  /  21 February 2011

Six strains of mice lacking a gene associated with fragile X syndrome show radically different behaviors though they share the same mutation, researchers reported in January in Autism Research.

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Left behind

by  /  18 February 2011

High school graduation marks the end of opportunities for social engagement and access to services for many young people with autism.

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‘Mind blindness’ affects moral reasoning in autism

by  /  17 February 2011

High-functioning adults with autism pass false belief tests with ease, but struggle with moral judgment in real-life situations.

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Molecular mechanisms: Mice model milder form of fragile X

by  /  16 February 2011

A partial mutation that leads to a milder form of fragile X syndrome causes deficits in learning and memory in mice, and alters the connections between their neurons, according to a study published in January in Neurobiology of Disease.

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