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Spectrum: Autism Research News

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Genes

Rare or common, inherited or spontaneous, mutations form the core of autism risk.

July 2012

Cognition and behavior: Maternal infection linked to anxiety

by  /  18 July 2012

Offspring born to pregnant rats with an activated immune system emit more distress calls when they receive electrical shocks than do controls, according to a study published 9 June in the Journal of Psychiatric Research.

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Genetics: Language disorder gene linked to autism

by  /  17 July 2012

A girl with autism has a spontaneous deletion in CMIP, a gene associated with specific language impairment, providing another genetic link between the two disorders. The case study was published 11 June in Autism Research.

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Geneticists join forces for autism sequencing push

by  /  16 July 2012

Researchers have launched an effort to yoke together disparate gene sequencing projects in the U.S., Canada and the U.K., aiming to double the number of known autism-related genes in the next three to four years.

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Expression data links gene candidates to autism

by  /  11 July 2012

Identifying genetic variants that affect the expression of other genes can enhance traditional gene association analyses and highlight candidate risk factors for autism, according to a study published 16 May in Molecular Autism.

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Molecular mechanisms: FMRP target linked to cognitive skills

by  /  11 July 2012

The protein missing in people with fragile X syndrome may activate the expression of a signaling protein dubbed NOS1 during prenatal development of brain regions involved in language and social skills, according to a study published 11 May in Cell.

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Exome sequencing identifies unknown disorders

by  /  9 July 2012

By sequencing the protein-coding region of the genome of a single affected family member, researchers were able to diagnose 20 percent of people in 85 consanguineous families with unknown neurodevelopmental disorders, according to research published 13 June in Science Translational Medicine.

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Brain hack

by  /  6 July 2012

The Allen Institute convened a five-day ‘hackathon’ to create new tools that take advantage of the petabytes of brain mapping data in the institute’s massive databases.

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Genetics: Study links MET gene to emotion recognition

by  /  6 July 2012

Researchers have linked the ability to recognize emotions from facial expressions to MET, a well-known autism gene, according to a study published 27 April in PLoS ONE.

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Gene expression analysis identifies risk genes for autism

by  /  5 July 2012

Analyzing how mutations in people with autism affect gene expression in blood-derived cells could help researchers pinpoint harmful mutations, according to research published 21 July in The American Journal of Human Genetics.

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Researchers debut ‘virtual microscope’ for mouse brain

by  /  4 July 2012

Researchers have released the first set of data from the Mouse Brain Architecture Project, which uses light microscopy to trace neuronal circuits in the mouse brain.

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