Tag: X chromosome

September 2018
News / Toolbox

New mouse model paves way for Rett syndrome treatments

by  /  7 September 2018

A new line of female mice may enable researchers to test gene-based therapies for Rett syndrome.

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March 2018
Deleting DNA repeats from fragile X neurons restores expression (right, red) of the gene silenced in the syndrome.
News

CRISPR tweak fixes genetic flaw in fragile X syndrome

by  /  29 March 2018

A modified version of the genetic engineering tool CRISPR may restore expression of the gene mutated in fragile X syndrome.

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October 2017
Brain scans of boys with fragile X syndrome fall into distinct groupings.
News

Brain scans reveal subtypes of fragile X syndrome in boys

by  /  30 October 2017

Differences in brain structure may distinguish boys with relatively mild features of fragile X syndrome from those with a severe form of the condition.

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Microscope image of neuronal injections in brain.
News

Two drugs ease features of autism syndromes in mice

by  /  11 October 2017

Drugs that block certain brain enzymes could help treat two conditions associated with autism.

1 Comment
Week of OctoberOct
2nd
2017
News / Spotted

Cannabis candidate; omega add-on; oxytocin control and more

by  /  6 October 2017

A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.

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August 2017
Week of JulyJul
31st
2017
News / Spotted

Autism unsurprised; diagnostic camouflage; Neanderthal legacy and more

by  /  4 August 2017

People with autism aren’t easily surprised, the social camouflage some girls and women with autism use may preclude diagnosis, and autism-related genes are rooted deep in human ancestry.

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March 2017
News

Muting X chromosome silencers may serve as remedy for Rett

by  /  30 March 2017

Manipulating pathways that help silence the X chromosome may help treat Rett syndrome, a condition closely related to autism.

0 Comments
Opinion / Viewpoint

Questions for Huda Zoghbi: Studying Rett in the rodent brain

by  /  14 March 2017

Removing the Rett syndrome gene, MeCP2, from distinct cells and brain regions reveals hidden features of the condition.

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April 2016
News

Mouse study links gene to some autism symptoms

by  /  22 April 2016

Mice missing a gene called PTCHD1 in a deep-seated brain structure have autism-like symptoms that ease with treatment.

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October 2015
Features / Deep Dive

The lost girls

by  /  19 October 2015

Misdiagnosed, misunderstood or missed altogether, many women with autism struggle to get the help they need.

36 Comments