Tag: macrocephaly

December 2019
a young girl has her height measured by a woman
News

Top autism gene tied to unusual skull, skeletal growth

by  /  12 December 2019

People with mutations in CHD8, a top autism gene, tend to be tall and have large heads.

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November 2019
News

Mouse study reveals overlooked target for autism therapies

by  /  20 November 2019

Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.

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Close-up of child's hand on wet window
News

Mutations in cancer gene tied to unique autism traits

by  /  14 November 2019

Autistic people who carry mutations in a gene called PTEN have distinct behavioral and motor problems.

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October 2019
News

Single molecule tracks with mutation’s path to autism, cancer

by  /  17 October 2019

A molecule made by mitochondria, the energy factories of cells, might help doctors forecast the impact of mutations in a top autism gene.

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March 2019
Opinion / Viewpoint

Analyzing postmortem brains for autism? Proceed with caution

by  /  5 March 2019

Any study of postmortem brains must control for artifacts, which are pervasive in brain tissue.

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November 2018
Toddle boy having his head measured in a medical setting.
News

Brain organoid study firmly links autism mutations to RhoA

by  /  7 November 2018

A cellular pathway that helps neurons grow and move during fetal development may drive the changes in head size in some autistic people.

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June 2018
Week of JuneJun
4th
2018
News / Spotted

Oversold diets; big brains explained; tracking CRISPR and more

by  /  8 June 2018

Benefits of diets for autism features remain unproven, variants of the same DNA region make brains big or small, and STAT announces a new CRISPR tracker.

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News

Growth spurt in head, skeleton mark autism in boys

by  /  6 June 2018

Boys with autism have smaller heads, are shorter and weigh less at birth than typical children do — but all that changes by age 3.

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April 2018
extra neuronal connections may sprout from the amygdala, a brain region governing fear
News

In autism, brain’s emotion hub begins with too many cells

by  /  6 April 2018

The amygdala, a brain region that governs emotions, may be enlarged and overly connected in children with autism, but it shrinks as the children grow up.

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January 2018
Neurons missing a part of chromosome 16 (left) are larger and have more branches than control neurons (middle); neurons with duplications of the region are small and sport short dendrites (right).
News

Lab-grown neurons showcase effects of autism mutations

by  /  15 January 2018

Neurons derived from people with mutations linked to autism display diverse abnormalities that may help explain the origins of these individuals’ features.

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