Tag: macrocephaly

April 2014
Only human: People carry 271 copies of a repeated DNA sequence, compared with 30 repeats in monkeys, 4 in dolphins and 1 in mice.
News

Repeats in human DNA may aggravate autism symptoms

by  /  21 April 2014

Certain DNA repeats that increased exponentially during human evolution are directly related to the severity of autism symptoms, according to a preliminary study published 20 March in PLoS Genetics.

0 Comments
Opinion / Viewpoint

The cerebellum’s surprisingly evolved role in autism

by  /  1 April 2014

Thought until recently to only coordinate motor skills, the cerebellum is involved in diverse cognitive functions such as language and social interaction, and may play a role in autism, says Emanuel DiCicco-Bloom.

11 Comments
March 2014
Opinion / Viewpoint

Emerging importance of chromatin in autism risk

by ,  /  18 March 2014

Sequencing studies over the past few years have made a dramatic and unexpected discovery: Many of the mutations in individuals with autism are in genes that regulate chromatin, which helps package DNA in the cell nucleus, say Gerald Crabtree and Aryaman Shalizi.

1 Comment
December 2013
Opinion / Viewpoint

Understanding contradictory connectivity reports in autism

by ,  /  10 December 2013

Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.

1 Comment
November 2013
News

Close look at autism-linked region reveals complex biology

by  /  27 November 2013

Deletion and duplication of the 16p11.2 chromosomal region have opposite effects on brain size, but produce similar alterations in the brain’s processing of sound. Researchers reported these and other unpublished findings at the 2013 Society for Neuroscience annual meeting in San Diego, painting a complex picture of the region’s role in autism.

0 Comments
News

SfN 2013 comes to a close

by  /  18 November 2013

A packed week of research at the 2013 Society for Neuroscience annual meeting in San Diego brought a flurry of breaking news and a creative combination of emerging research tools.

1 Comment
News

Neurons made from people with autism show distinct markers

by  /  12 November 2013

Researchers have created neurons from the skin cells of children with autism, according to an unpublished study presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego. These neurons show several distinct features, including elevated markers of inhibitory signaling.

4 Comments
News

Study traces link between social behavior, brain overgrowth

by  /  11 November 2013

Social difficulties and early overgrowth of the brain are trademarks of autism, yet a direct connection between the two has been elusive. One group of researchers may have found a link between the two symptoms and a way to treat both at once, they reported Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.
 

0 Comments
October 2013
News / Profiles

Elliott Sherr: Coaching teams to tackle autism’s mysteries

by  /  10 October 2013

Elliott Sherr is unraveling the effects of genetics and brain structure in a handful of disparate disorders that each illuminates some aspect of autism.

2 Comments
August 2013
News

In autism, head and body size varies with gender

by  /  29 August 2013

Girls with autism tend to have smaller heads and bodies than their typically developing peers, whereas boys with the disorder tend to have average-sized heads and slightly larger bodies, report two studies published in July.

1 Comment