Tag: macrocephaly

November 2014
Opinion

Mouse study sheds light on maternal infection, autism link

by  /  21 November 2014

A new study points to a possible link between inflammation in the womb, brain overgrowth and the behavioral impairments seen in autism.
 

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October 2014
News

Scientists catalog effects of PTEN mutations in autism

by  /  27 October 2014

People with autism who have mutations in a gene called PTEN have a distinct profile of cognitive impairments and structural abnormalities in the brain. The profile, published 7 October in Molecular Psychiatry, points to a subtype of autism with these features.

5 Comments
News

Autism-linked deletion sparks symptoms via many genes

by  /  23 October 2014

Deletion or duplication of 16p11.2, a chromosomal region linked to autism, may trigger symptoms via the interactions of genes both within and outside the region at a key point in development. Researchers presented these preliminary results Sunday at the 2014 American Society of Human Genetics Annual Meeting in San Diego.

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News

Studies question link between head circumference, autism

by  /  16 October 2014

Having an enlarged head in early childhood is not a reliable marker of autism, according to two new studies that tracked changes in head and body size in children over time.

3 Comments
News

New mouse model mimics brain abnormalities in autism

by  /  6 October 2014

Mice with mutations in the autism-linked gene WDFY3 have enlarged brains reminiscent of those seen in some children with autism, according to a study published 8 September in Nature Communications.

1 Comment
July 2014
News

Cluster of symptoms reveals gene’s link to autism subtype

by  /  3 July 2014

CHD8, a gene that regulates the structure of DNA, is the closest thing so far to an ‘autism gene,’ suggests a study published today in Cell. People with mutations in this gene all have the same cluster of symptoms, including autism.

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Opinion / Q&A

Questions for Nicholas Katsanis: Fishing for autism genes

by  /  1 July 2014

Cell biologist Nicholas Katsanis explains why zebrafish have been key in studying a chromosomal region linked to autism.

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June 2014
Opinion / Viewpoint

How to evaluate new medications for autism

by  /  10 June 2014

There are no available medications for treating autism’s core symptoms, but there are several candidates in clinical trials. Jeremy Veenstra-VanderWeele describes the factors researchers must take into account when developing drugs for the disorder.

7 Comments
May 2014
News

Autism-linked chromosomal region regulates brain size

by  /  16 May 2014

The genes in 16p11.2, the autism-linked region on chromosome 16, may directly affect brain size early in development, according to unpublished research presented Thursday at the 2014 International Meeting for Autism Research in Atlanta.

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April 2014
News

Molecular mechanisms: Mutant mice seek out social contact

by  /  29 April 2014

Male mice that carry a specific mutation in the autism-linked PTEN gene have enlarged brains and show heightened interest in other mice, according to a study published 7 February in Human Molecular Genetics.

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