Tag: macrocephaly

May 2016
News

Mouse with key autism mutation defies expectations

by  /  14 May 2016

Mice with a mutation in CHD8, the top autism gene, show no signs of any of the condition’s core features.

1 Comment
June 2015
News

Diverse features found for autism-linked chromosome changes

by  /  29 June 2015

The first in-depth look at people with alterations in the 1q21.1 chromosomal region reveals a range of features, from problems with fine motor skills to autism.

1 Comment
News

Study picks up autism broadcast in tiny antennae on cells

by  /  8 June 2015

Mutations in a section of chromosome 16 that is linked to autism have an unexpected effect: They alter the miniscule hairs, or cilia, that adorn the surface of all cells. The findings suggest that problems with these cilia may contribute to autism.

0 Comments
April 2015
News

Autism-linked DNA deletion may derail brain development

by  /  2 April 2015

Missing a swath of chromosome 16 with strong ties to autism disrupts proteins crucial for early brain development. The findings open the door to targeted interventions.

1 Comment
March 2015
News

Gene defect may signal distinctive form of autism

by  /  30 March 2015

Mutations in the gene DYRK1A underlie a type of autism marked by an unusually small head. The new work expands the breadth of symptoms included under the autism umbrella.

1 Comment
January 2015
News

Surplus of neurons spurs autism traits in mice

by  /  15 January 2015

Fetal mice that have too many neurons grow to show social deficits and repetitive behaviors. The finding, reported 11 December in Cell Reports, debuts a mouse model of autism that’s based on a biological abnormality seen in some people with the disorder.

0 Comments
December 2014
Features / Special Reports / 2014 Year in review

Editors’ picks: Our favorite stories from 2014

22 December 2014

This year was full of big headlines in autism research. But the biggest stories aren’t necessarily the best — here are some gems you may have missed over the year.

0 Comments
News

Brains of people with autism show altered growth with age

by  /  11 December 2014

Several brain regions in people with autism become enlarged earlier than usual during childhood and shrink too soon during adulthood, finds an eight-year imaging study.

3 Comments
News

Facial measurements resurface in search for autism clues

by  /  8 December 2014

A group of scientists is using fast, accurate and minimally invasive measurement systems to revive the once-tedious trade of dysmorphology, or the study of unusual facial features, in autism.

2 Comments
November 2014
Features / Deep Dive

Genetics first: A fresh take on autism’s diversity

by  /  24 November 2014

Each child with autism is different from the next. One approach rapidly gaining momentum makes sense of this diversity by grouping children together based on their genetics, then looking for patterns in their symptoms. The long-term aim: personalized treatments for each subtype of autism.

0 Comments