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Spectrum: Autism Research News

Tag: intellectual disability

November 2010

Genetics: Two families link new gene to autism

by  /  15 November 2010

Researchers have narrowed down a genetic region associated with autism to one protein, cadherin 8, that helps bind cells together, according to a study published online in October in the Journal of Medical Genetics. This is the first time CDH8, the gene that encodes this protein, has been associated with autism.

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Genetics: Gene family linked to language and autism

by  /  5 November 2010

Loss of activity of FOXP1, a member of a family of genes that regulate gene expression, leads to general behavioral defects, including delays in language, according to a study published in November in The American Journal of Human Genetics.

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October 2010

Genetics: Autism and attention deficit share mutations

by  /  15 October 2010

Individuals with attention deficit hyperactivity disorder (ADHD) have a higher rate of DNA duplications and deletions, including some in regions linked to autism and schizophrenia, according to a study published 23 October in The Lancet.

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Science by zodiac

by  /  5 October 2010

Research has hinted that the season of a child’s birth may play some role in his or her risk of developing various neuropsychiatric disorders. But it’s the season of conception that really matters, a new study suggests.

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September 2010

Genetics: Common mutation linked to risk of mental disorders

by  /  27 September 2010

A common variation within a region on chromosome 16 puts a large proportion of the general population at risk for intellectual disability, according to a study published in August in Nature Genetics.

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X-linked gene increases autism risk in boys

by  /  16 September 2010

A newly characterized gene on the X chromosome may be disrupted in up to one percent of people with autism, researchers reported Wednesday in Science Translational Medicine.

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August 2010

Social factors may drive the spike in autism cases

by  /  27 August 2010

Changes in diagnostic practices, more active neighborhood networks, and an increase in the number of older parents may all contribute to the massive rates of autism in California, says a group of social scientists. But the numbers still don’t add up.

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July 2010

Study finds weak genetic link between autism and intelligence

by  /  20 July 2010

Autism and intellectual disability often occur together, but in most cases that overlap is not genetic, according to a study of twin pairs published in the American Journal of Medical Genetics. Unraveling this link might help researchers pinpoint brain circuits involved in both conditions, and better understand the diversity of symptoms in the autism spectrum, experts say.

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Chromosome 7 segment gives clues to complex social behavior

by  /  12 July 2010

Individuals carrying an extra copy of the genetic region that’s missing in Williams syndrome — which causes mental retardation and a hyper-friendly personality — have language impairments and other autism-like social difficulties, according to a wave of new research on this duplication syndrome.

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Deep sequencing questions role of imprinted genes in autism

by  /  8 July 2010

The mouse brain has more than 1,300 regions for which the copy from one parent is expressed more often than the one from the other parent, according to two studies published today in Science. These so-called imprinted genes have been proposed to cause some cases of autism, but the researchers say their findings do not support that theory.

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