Skip to main content

Spectrum: Autism Research News

Tag: intellectual disability

June 2010

Simple pathway

by  /  24 June 2010

A study of a rare form of epilepsy found in Amish groups adds heft to the idea that mTOR — a much-studied hub in a massive network of brain cell proteins — is an important biochemical player in autism.

2 Comments

Autism marked by copy number changes in coding regions

by  /  11 June 2010

People with autism harbor more copy number variants (CNVs) — deletions or duplications of large chunks of DNA — compared with controls, but only in the protein-coding regions of the genome, researchers reported Wednesday in Nature. The study also pinpointed more than 100 new risk genes for autism.

1 Comment
May 2010

Williams syndrome precludes racial bias, study finds

by  /  20 May 2010

Children with Williams syndrome — a rare genetic disorder that leads to mental retardation and overt friendliness — hold stereotypes based on gender, but not race, according to a report published in Current Biology. Because those with Williams syndrome don’t have social fear, the study suggests racial stereotypes are based partly on fear.

0 Comments

Study implicates cell-adhesion proteins in autism

by  /  18 May 2010

Variations in two genes needed to form connections between brain cells may be associated with autism spectrum disorder, according to a study published 25 March in Molecular Autism. Some variants in the genes seem to increase susceptibility to autism, whereas others protect children from developing the disorder.

0 Comments

Mouse models reveal workings of neuroligin-1

by  /  4 May 2010

Researchers are tinkering with mouse models to investigate the function of a protein that helps wire neurons together and that has repeatedly been linked to autism. Three such reports of the protein, neuroligin-1, have appeared this year.

0 Comments
March 2010

Evan Eichler: Following his instincts to autism ‘hotspots’

by  /  22 March 2010

With an openness to collaboration and a healthy dose of daring, Evan Eichler has turned his offbeat interest in repeat DNA sequences into a new understanding of how genomes evolve, expediting the search for genes disrupted in autism.

0 Comments

Two-hit wonder

by  /  17 March 2010

We know that carrying one specific DNA variant can increase your risk of autism. What if you carry two?

0 Comments

Clinical, animal studies probe DISC1’s role in autism

by  /  1 March 2010

Several genetic and animal studies in the past year have found intriguing ties between autism and DISC1, one of the oldest candidate genes for psychiatric disorders.

0 Comments
November 2009

Double trouble

by  /  17 November 2009

Rare mutations that increase the risk of neuro-psychiatric diseases usually occur in only one copy of a gene. What happens when both copies are mutated?

0 Comments

Autism study zooms in on five-gene strip on chromosome 16

by  /  10 November 2009

Genetic analysis of one Belgian family with a history of autism has pinpointed a piece of DNA on chromosome 16, within a segment thought to be missing in about one percent of all cases of autism. The unpublished data was presented on Saturday at the World Congress of Psychiatric Genetics in San Diego.

0 Comments