Skip to main content

Spectrum: Autism Research News

Tag: cortex

March 2023
MRI scan with a section enlarged to display the scan's grey-white boundary.

Brain imaging do-over offers clues to field’s replication problem

by  /  13 March 2023

Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.

Comments
February 2023
an image of a neuron

Neurons struggle to spike without fragile X gene

by  /  17 February 2023

FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information.

Comments
January 2023
Lab images of cilia.

Autism and the cell’s antennae

by  /  4 January 2023

Many autism-linked genes are somehow tied to cilia, the tiny hair-like sensors that stud a cell’s surface. But the question remains whether, and how, cilia differences contribute to the condition.

Comments
November 2022
Light micrograph of microglia cells stained with Rio Hortega’s silver carbonate method.

Autism’s sex bias tied to glial, immune cell gene expression

by  /  22 November 2022

The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

Comments
Image of organoids modeling CDKL5 deficiency disorder.

Organoids identify potential therapies, circuit flaws for autism-linked syndromes

by  /  21 November 2022

Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

Comments
October 2022
A transplanted human organoid labeled with a fluorescent protein in a section of the rat brain.

Human cortical organoids forge functional circuits in rat brains

by  /  12 October 2022

The transplanted cells integrate into living animals’ neural circuitry and influence behavior.

Comments
September 2022
A set of 4 multicolored brain scans showing development of cortical surface area.

New mapping method reveals subtleties of brain development

by  /  21 September 2022

The machine-learning approach could help identify how brain structure differs between autistic and non-autistic infants, the researchers say.

Comments
Dr. Edgar helps the participant prepare for the magnetoencephalography (MEG) exam.

Auditory cortex may develop early in autism

by  /  16 September 2022

A well-studied brain response to sound appears earlier than usual in young children with autism.

Comments
August 2022
A large MRI scan of a human brain, with a grid of 15 smaller MRI scans to its left

Chromosome 22 mutations leave telltale marks on brain development in autistic people

by  /  24 August 2022

Many brain regions develop differently between people with 22q11.2 duplications and deletions, and those trajectories also vary with a person’s diagnosis.

Comments
Several strands of DNA with different openings at different points to show different functions for the same gene at different points in time

‘Double duty’ autism-linked genes upend conventional characterizations

by  /  23 August 2022

What these genes do and how they affect autism depends on when in development they’re studied, despite what classic ‘gene ontology’ analyses say.

Comments