Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.
Spectrum: Autism Research News
The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.
Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.
The transplanted cells integrate into living animals’ neural circuitry and influence behavior.
The machine-learning approach could help identify how brain structure differs between autistic and non-autistic infants, the researchers say.
Many brain regions develop differently between people with 22q11.2 duplications and deletions, and those trajectories also vary with a person’s diagnosis.
What these genes do and how they affect autism depends on when in development they’re studied, despite what classic ‘gene ontology’ analyses say.