The chimeric mouse model could provide a more realistic way to study microglia’s roles in brain conditions such as autism.

Compared with their non-autistic peers, young autistic girls have a thicker cortex that thins more quickly with age.

By imaging and recording synaptic activity in living mouse embryos for the first time, new research reveals previously unknown patterns of development and hints at how those patterns are disrupted in autism.

The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.

Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.

FMR1 loss impairs sodium channels, hindering mouse neurons from generating the electrical signals needed to transmit information.

Many autism-linked genes are somehow tied to cilia, the tiny hair-like sensors that stud a cell’s surface. But the question remains whether, and how, cilia differences contribute to the condition.

The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

An analysis of 11 cortical regions shows anterior-to-posterior shifts in gene expression linked to autism.