The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.
Spectrum: Autism Research News
Mice and zebrafish missing the GIGYF1 gene show social traits reminiscent of autism, though the molecular underpinnings are unclear.
Blocking the enzyme, called TOP2A, in embryos makes the animals less inclined to seek companionship later in life.
Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.
Scott describes his work on sound processing differences in the brains of zebrafish that model fragile X syndrome.
The gene, YTHDF2, has not previously been linked to autism.
The gene, YTHDF2, may be one of several that contribute to an autism subtype marked by an unusually big brain.
Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.