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Tag: zebrafish

May 2021
News

Stimulant restores cell signaling, eases behavior issues in animals missing autism gene

by  /  28 May 2021

Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.

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January 2021
News

Zebrafish lacking oxytocin receptors skip school

by  /  13 January 2021

Model fish seem to spend more time swimming solo than wildtype zebrafish do, and neurochemicals in their brains respond differently to social interactions.

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Colorful CT scan of a zebrafish head.
News

Zebrafish strains reveal broad effects of autism genes

by  /  11 January 2021

Mutations in autism-linked genes lead to a variety of changes in brain activity, sensory perception and sleep-wake cycles in zebrafish.

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November 2020
SYNGAP1 protein between neurons.
News

Reactions from the 2020 SYNGAP1 Scientific Conference

by  /  25 November 2020

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

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Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.
News

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

by  /  24 November 2020

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

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September 2020
Zebrafish embryos with various deformities.
News / Toolbox

CRISPR technique knocks down gene expression in animal embryos

by  /  2 September 2020

A new method that suppresses gene expression in the embryos of fish and mice may help researchers study autism genes in early development.

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November 2019
Neurons in zebrafish spinal motor circuit
News / Toolbox

New technique follows single neurons from birth to brain circuit

by  /  1 November 2019

A new technique lets researchers watch brain circuits as they’re being built, starting from the individual neurons birth.

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October 2019
Neurons in a fish glow green.
News

Erasable sensor of brain activity could reveal roots of social behavior

by  /  23 October 2019

Researchers unveiled a reversible new technique for labeling active neurons in freely moving animals.

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September 2019
Glowing neurons in the transparent young zebrafish highlight activity in its brain and muscles.
News / Toolbox

Zebrafish show true colors as models for autism sleep studies

by  /  13 September 2019

Sleeping zebrafish show two patterns of neuronal activity that are analogous to those in people.

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synapse populations analysis--micrograph shows neurons in green in colorful network
Opinion / Viewpoint

How studying sleep in animals could unearth autism’s roots

by  /  3 September 2019

Sleep problems may contribute to autism’s underlying biology — a connection that scientists can study in animal models.

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