A new approach allows researchers to visualize individual neurons in the small, clear brains of larval zebrafish as they interact with their surroundings, according to a study published 9 May in Nature.
Researchers have created sponge-like assemblies of hundreds of thousands of short fragments of RNA, which can be used to dampen the expression of certain genes, according to a study published 26 February in Nature Materials.
A gene that changed rapidly after the human genome diverged from that of Neanderthals plays a critical role in brain development, according to unpublished results presented Thursday at the International Congress of Human Genetics in Montreal, Canada.
Researchers have devised a way to inactivate genes in zebrafish embryos, creating a collection of hundreds of mutant fish lines in which gene function can be explored. The technique was published online 8 May in Nature Methods.
Hazel Sive is a classically-trained embryologist and developmental biologist, and an expert in zebrafish genetics. She is using the small, transparent fish embryos for research on autism — an odd choice, as they obviously lack the complex behavioral repertoire seen in the disorder.