Tag: zebrafish

May 2012
News / Toolbox

Sponges made from RNA can knock down gene expression

by  /  9 May 2012

Researchers have created sponge-like assemblies of hundreds of thousands of short fragments of RNA, which can be used to dampen the expression of certain genes, according to a study published 26 February in Nature Materials.

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November 2011
Opinion

Mouse monopoly

by  /  25 November 2011

There are a host of problems with laboratory rodents that scientists rarely talk about, argues a fascinating series of articles in Slate magazine.

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October 2011
News

Fast-evolving gene is key player in brain development

by  /  14 October 2011

A gene that changed rapidly after the human genome diverged from that of Neanderthals plays a critical role in brain development, according to unpublished results presented Thursday at the International Congress of Human Genetics in Montreal, Canada.

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September 2011
Opinion

Model systems

by  /  23 September 2011

The more we find out about human genetics, the more valuable model organisms are likely to become, say autism researchers.  

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August 2011
Opinion / Viewpoint

How fish can help find causes of autism

by ,  /  29 August 2011

Zebrafish share genes and pathways with humans, making them a useful tool to identify the genes that malfunction in autism, says expert Hazel Sive.

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May 2011
News / Toolbox

New tool links gene to function in zebrafish

by  /  25 May 2011

Researchers have devised a way to inactivate genes in zebrafish embryos, creating a collection of hundreds of mutant fish lines in which gene function can be explored. The technique was published online 8 May in Nature Methods.

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Opinion

Unequal rights

by  /  3 May 2011

Things are getting better for women in science, but we are still far from a world in which gender is irrelevant.

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November 2010
News / Profiles

Hazel Sive: A fish tale

by  /  29 November 2010

Hazel Sive is a classically-trained embryologist and developmental biologist, and an expert in zebrafish genetics. She is using the small, transparent fish embryos for research on autism — an odd choice, as they obviously lack the complex behavioral repertoire seen in the disorder.

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News

Fish tale implicates language gene in autism

by  /  18 November 2010

Reducing the levels of CNTNAP2 — a gene implicated in both autism and language impairment — in zebrafish leads to a decrease in neurons that dampen signals in the brain, according to unpublished data presented Tuesday at the Society for Neuroscience annual meeting in San Diego.

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May 2010
News / Toolbox

Creatures great and small

by  /  18 May 2010

Among animal models of autism, the mouse reigns supreme. But could much simpler species — flies, bees, worms, fish — also teach us about the disorder?

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