Tag: zebrafish

June 2016
News / Toolbox

Gene-editing tool used to map lineage of cells

by  /  29 June 2016

Researchers have repurposed CRISPR, the popular gene-editing tool, for tracing cell lineages in whole organisms.

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News / Toolbox

‘Magneto’ manipulates behavior of freely moving mice

by  /  22 June 2016

A magnetically sensitive protein allows researchers to switch on neurons in freely moving mice and zebrafish.

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May 2016
News / Toolbox

New tool lights up edits to zebrafish genome

by  /  4 May 2016

A new gene-editing system allows researchers to rewrite lengthy stretches of DNA in zebrafish and identify the mutant fish with ease.

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January 2016
News

Hyperactive fish point to new drug treatments for autism

by  /  29 January 2016

A drug that mimics estrogen eases hyperactivity in zebrafish lacking the autism-linked gene CNTNAP2. The results highlight the potential of the tiny fish for screening autism treatments.

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October 2015
News

New clues connect chemical messenger to autism

by  /  16 October 2015

New evidence implicates the neurotransmitter glycine, which dampens brain signals, in autism.

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News / Toolbox

New method highlights activity in zebrafish brains

by  /  14 October 2015

A new technique gives researchers a window into the constellation of neurons that fire as zebrafish larvae swim in a dish.

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June 2015
News

Study picks up autism broadcast in tiny antennae on cells

by  /  8 June 2015

Mutations in a section of chromosome 16 that is linked to autism have an unexpected effect: They alter the miniscule hairs, or cilia, that adorn the surface of all cells. The findings suggest that problems with these cilia may contribute to autism.

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Opinion

Startled fish help sound out sensory overload in autism

by  /  8 June 2015

There is some evidence that neural habituation — the process by which neurons get used to sensory stimuli — goes awry in autism. Mutant fish may help us understand the sensory sensitivities that often accompany the disorder, says Alan Packer.

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April 2015
News

Autism-linked DNA deletion may derail brain development

by  /  2 April 2015

Missing a swath of chromosome 16 with strong ties to autism disrupts proteins crucial for early brain development. The findings open the door to targeted interventions.

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March 2015
News

Women with severe autism point to new gene candidates

by  /  26 March 2015

Looking in families with a history of severe autism among women, researchers have unearthed 18 new candidate genes for the disorder. One of these genes, delta-catenin, plays a critical role in brain development, researchers reported yesterday in Nature.

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