Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.
Spectrum: Autism Research News
Tag: social difficulties
Genetics strongly influences some aspects of the monkey’s social behavior, including tendencies to solicit grooming and sit or play alone.
New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.
Compared with a previous mouse strain, a new model better reflects some of the difficulties that people with a rare autism-related syndrome experience, and may help identify biomarkers of the syndrome.
The first animal model of MYT1L syndrome suggests that fast-maturing neurons lead to the unusually small brains, social deficits and other traits seen in people with the condition.
Autistic people have a higher-than-average chance of developing a neurodegenerative condition, according to a few studies. Some scientists are searching for proof — work that could also improve care for older autistic adults.
The finding that MDMA and an experimental serotonin agonist increase sociability across six different model mice suggests that disparate autism-linked mutations converge on the same underlying pathways.
When probing the circuits underlying social behavior in animal models of autism, researchers should consider potentially confounding variables, use multiple behavioral assays and report results in a descriptive and unbiased manner.