Changes to mitochondrial DNA spur autism-like traits in mice
Mice with a mutation in their mitochondrial DNA show altered brain activity, repetitive behaviors and reduced sociability, according to a new study.
Mice with a mutation in their mitochondrial DNA show altered brain activity, repetitive behaviors and reduced sociability, according to a new study.
Mice missing a copy of MAGEL2 have trouble discerning between a familiar mouse and an unfamiliar one; treating them with the social hormone vasopressin reverses this deficit.
Mice missing a copy of the autism-linked gene PTEN show a reduced preference for social interaction, possibly due to atypically large, overconnected dopamine neurons. Easing the overconnection may alleviate this trait.
Young male rats can recognize rats they’ve recently met, whereas young females treat new acquaintances like strangers, research shows.
Two types of neurons process social information, a new mouse study suggests, but only one is disrupted in mice missing the autism-linked gene FMR1.
Some social behaviors associated with autism are heritable, but the extent to which genes and the environment influence these behaviors changes as a child grows.
This is part 2 of Owen’s story. It tracks his early progress in treatment for autism. Part 1 described his difficult path to a diagnosis.
The more children with autism tune in to and communicate with others as toddlers, the stronger their conversation skills are later in childhood.
Looking for signs of autism in characters from history and literature can offer insight into society’s changing perceptions through time — but it can also increase the risk of stigma against people with the condition.
Autism is unusually common among blind people, and children with autism are more likely to have vision problems than their typical peers. Understanding why could lead to better therapies for autism for autism.