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Spectrum: Autism Research News

Tag: social difficulties

January 2023
Research image showing neuronal activity in mice exposed to high-frequency sounds.

Missing mechanism helps solve fragile X protein mystery

by  /  24 January 2023

Cells from people with fragile X syndrome overproduce — but don’t accumulate — proteins. New work suggests that excessive protein breakdown may account for this discrepancy, and explain some of the syndrome’s traits.

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December 2022
A photograph of zebrafish in a lab environment.

DNA unwinder tied to social behaviors in mice, zebrafish

by  /  16 December 2022

Blocking the enzyme, called TOP2A, in embryos makes the animals less inclined to seek companionship later in life.

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November 2022
Still image from video of zebrafish swimming in small enclosures.

Zebrafish social behavior swims into mainstream

by  /  17 November 2022

New studies bolster the idea that zebrafish models can say something meaningful about social behavior in autism.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: COVID-19 conclusions; diagnosis duplication; oxytocin again

by  /  10 November 2022

This month’s newsletter explores the pandemic’s effects on autism rates, trends in co-occurring mental health conditions, and the impact of intranasal oxytocin.

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October 2022
Mouse brain slices showing the effects of SHANK2 and SHANK3 deletions.

Double SHANK knockout highlights brain circuit’s social role

by  /  19 October 2022

Mice missing the autism-linked SHANK2 and SHANK3 genes in their retrosplenial cortex have trouble distinguishing between novel and familiar mice.

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September 2022
Noah Sasson, a thin white man, stands in a courtyard with his hands in his pockets.

Noah Sasson: Connecting with the autistic community

by  /  15 September 2022

Intentional interactions with autistic people led Sasson to refocus his research.

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David Mandell sits on the steps of a school.

How losing a parent helped shape David Mandell’s approach to autism research

by  /  6 September 2022

Autism’s “fearless” researcher takes on the big questions.

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July 2022

Mouse study links dopamine in cerebellum to social behavior

by  /  6 July 2022

The signaling molecule’s social role in the ‘little brain’ involves Purkinje neurons in the Crus I and Crus II regions, a new study reveals.

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hand points to pause button shape made from pills

Forging a path for vasopressin drugs for autism: Q&A with Suma Jacob

by  /  5 July 2022

After the vasopressin antagonist balovaptan flopped in a late-stage clinical trial, Suma Jacob and her colleagues took stock of all the factors that might have complicated the results.

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June 2022
two toddlers, a boy and a girl, draw animals on a glass window in thin lines of blue, green and magenta.

Autism’s sex bias disappears after tracking trajectories

by  /  22 June 2022

The male sex bias in autism may in large part be a product of how common diagnostic tools measure traits in boys versus girls at a single point in time, according to a new study.

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