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Tag: SNPs

August 2013
Opinion

Negative result

by  /  30 August 2013

Oxytocin may well have established its reputation as the ‘social hormone’ in the popular imagination, but it has no effect on symptoms in children with autism, according to a study published 26 July in the Journal of Autism and Developmental Disorders.

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Opinion / Viewpoint

How gender influences the autism brain

by ,  /  27 August 2013

Understanding the basis of sexual dimorphism in autism may not only inform our treatment of this condition, but may translate to therapies for many other mental illnesses, say Nirao Shah and Devanand Manoli.

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News

Genetics: Methyl groups on DNA modify Rett symptoms

by  /  20 August 2013

Methylation — modifications to DNA that regulate gene expression — may explain why identical twins with the same Rett syndrome mutation have different symptoms, according to a study published 21 June in PLoS One.

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News / Toolbox

Subgroups improve genetic analysis of autism

by  /  14 August 2013

Researchers can increase the power of studies that link genetic variants to autism by factoring in potential subgroups of the disorder, according to a report published 26 June in PLoS One.
 

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July 2013
News / Toolbox

Genetics algorithm reveals mosaic mutations

by  /  10 July 2013

A new software tool detects chromosomal alterations present in only a subset of cells in the body. This method, described 31 May in BMC Genomics, may help reveal mosaicism’s contribution to neurological disorders.

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News

Clinics unroll genome tests for undiagnosed disorders

by  /  8 July 2013

Two university-based clinics have debuted large programs that rely on sequencing to diagnose genetic disorders, including developmental disorders such as autism.

2 Comments
June 2013
News / Toolbox

Analysis probes literature for autism-linked gene culprits

by  /  26 June 2013

By combining bioinformatics techniques with an analysis of gene expression, researchers have identified 30 candidate genes for autism, according to a study published 28 May in Translational Psychiatry.

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April 2013
Opinion / Viewpoint

Slicing the genetic pie

by ,  /  5 April 2013

Jason Stein and Daniel Geschwind analyze how different types of genetic variation contribute to autism risk.

6 Comments
March 2013
Opinion / Viewpoint

Promise and pitfalls of induced stem cells for autism

by ,  /  26 March 2013

Induced pluripotent stem cells, which have the ability to become any cell type, including neurons, offer a powerful way to study neuropsychiatric disorders. But for this approach to reach its full potential, researchers must first address several challenges, such as variability between cell lines, say Flora Vaccarino and Jessica Mariani.

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Opinion / Viewpoint

Rho family of enzymes at crossroads of autism

by  /  12 March 2013

A number of autism risk factors converge on one cellular pathway: abnormal remodeling of the cell’s structural systems through the signaling protein Rho, says SFARI’s associate director for research, Alan Packer.

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