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Spectrum: Autism Research News

Tag: SNPs

October 2022
Conceptual illustration of two DNA helixes with several overlapping portions showing common and differing genes.

Genome scan spots common variant differences between autism and ADHD

by  /  12 October 2022

Common variants in five regions of the genome may determine whether someone has one condition versus the other.

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July 2022

New resource maps gene expression, regulation in neuron subtypes

by  /  1 July 2022

The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.

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May 2022

Information loss may weaken autism genetic scores

by  /  13 May 2022

Even the best data practices and technology drop key variants in attempts to predict autism likelihood.

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December 2021
Nighttime crowded Shanghai street scene with illumination from electric and neon signs.

New resource tracks genetic variations in Han Chinese populations

by  /  9 December 2021

An online database called NyuWa catalogs genetic variations among nearly 3,000 individuals and provides a comprehensive reference genome for the Han people.

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September 2021
Four brains showing areas affected by the X chomosome in yellow

X chromosome exerts extra influence on brain development

by  /  15 September 2021

The X chromosome holds stronger-than-expected genetic sway over the structure of several brain regions. The genes that may underlie this oversized influence have ties to autism.

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July 2021

Patchwork mutations present a new frontier for autism research

by  /  12 July 2021

Mosaic mutations, which affect only some of the body’s cells, play a small but meaningful role in autism. Though they are difficult to study, researchers are working to master their complexity.

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June 2021
Micrograph of two developing axons, one with one copy of TSC2 gene and the other with two copies.

Disrupted cell skeletons may explain brain wiring changes in autism-linked condition

by  /  28 June 2021

Neuronal axons ignore guidance cues after a mutation in the gene TSC2 disrupts signaling through RhoA, a protein regulated by many autism-linked genes.

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February 2021

Genetic variants in protein target sites may contribute to autism

by  /  12 February 2021

Mutations that disrupt binding sites in RNA molecules may play a role in autism and a variety of psychiatric conditions, according to a new study.

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September 2020
Colorful chart showing variants in chromosomes.

Scan of genomes for inherited variants lays bare new autism candidate

by  /  10 September 2020

Lowered expression of a gene called DDHD2 may increase a person’s likelihood of having autism, according to a new analysis.

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January 2020
Variants linked to multiple conditions, including autism, tend to appear in genes that influence brain development, as shown in this chart in blue and grey.

Autism may share inherited variants with other psychiatric conditions

by  /  13 January 2020

Some of the inherited variants implicated in autism also increase the odds of schizophrenia, bipolar disorder, depression or attention deficit hyperactivity disorder.

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