The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.
Spectrum: Autism Research News
An online database called NyuWa catalogs genetic variations among nearly 3,000 individuals and provides a comprehensive reference genome for the Han people.
The X chromosome holds stronger-than-expected genetic sway over the structure of several brain regions. The genes that may underlie this oversized influence have ties to autism.
Mosaic mutations, which affect only some of the body’s cells, play a small but meaningful role in autism. Though they are difficult to study, researchers are working to master their complexity.
Neuronal axons ignore guidance cues after a mutation in the gene TSC2 disrupts signaling through RhoA, a protein regulated by many autism-linked genes.
Mutations that disrupt binding sites in RNA molecules may play a role in autism and a variety of psychiatric conditions, according to a new study.
Lowered expression of a gene called DDHD2 may increase a person’s likelihood of having autism, according to a new analysis.
Some of the inherited variants implicated in autism also increase the odds of schizophrenia, bipolar disorder, depression or attention deficit hyperactivity disorder.
A new method enables researchers to test algorithms for spotting genes that contribute to a trait or condition.