Tag: rats

March 2014
News / Toolbox

Come-hither rat cry could measure social interest

by  /  5 March 2014

When navigating a maze, rats move toward happy rodent sounds and away from those signaling alarm, according to a review published 4 February in the Journal of Neuroscience Methods. The method could be used to assay social behavior in rodent models of autism.

February 2014

Cognition and behavior: Epilepsy drug alters rodent gut

by  /  14 February 2014

In utero exposure to the epilepsy drug valproic acid, which ups the risk of autism, may alter the composition of gut bacteria in rodents, according a study published 11 December in Brain Behavior and Immunity.


Drug calms overly excitable brains in autism rodent models

by  /  10 February 2014

The blood pressure drug bumetanide normalizes a deficit in brain activity in two rodent models of autism, according to a study published last week in Science. The study hints at a mechanism underlying the drug’s benefits for people with autism.

January 2014
Opinion / Viewpoint

Intense world theory raises intense worries

by ,  /  21 January 2014

The ‘intense world theory’ of autism, which has attracted much interest from the popular press, has received very little academic scrutiny. Uta Frith and Anna Remington ask: Is it as positive as it purports to be, and what does it mean for autism?

November 2013

Guinea pigs enter rat race for autism models

by  /  13 November 2013

Guinea pigs have advantages over other rodent species commonly used to model disorders such as autism, according to preliminary research published Tuesday at the Society for Neuroscience annual meeting in San Diego.

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With training, autism rat models overcome hearing problems

by  /  11 November 2013

Rat models of autism have a weak and sluggish brain response to speech sounds, but behavioral training can improve their performance. The unpublished results, presented Sunday at the 2013 Society for Neuroscience annual meeting in San Diego, suggest that a similar approach may benefit people with the disorder.

September 2013
News / Toolbox

Rats armed to catch up to mice as top mammalian model

by  /  4 September 2013

Researchers have developed a method to engineer rats so that they lack a certain gene in only select regions of the brain, they report in the July issue of Nature Methods.

April 2013

Molecular mechanisms: Rats could model autism gender bias

by  /  9 April 2013

Prenatal exposure of rats to the epilepsy drug valproic acid leads to behavioral and brain features that resemble autism, in males more than in females, according to a study published in the March issue of the Journal of Neurochemistry.

February 2013
News / Toolbox

Researchers carve out map of rodent brain

by  /  13 February 2013

Researchers have divided the rat brain into 26 structures that are present from birth to adulthood and that can be seen using brain imaging, according to a study published 15 February in Neuroimage.