Tag: rats

February 2017
News

Rats with mutant SHANK genes show autism-like behaviors

by  /  16 February 2017

Researchers have engineered two new rats with mutations in a family of genes that function at neuronal junctions, they reported today at the 2014 International Meeting for Autism Research in Atlanta.

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November 2016
News

Stem cell transplant makes rats more social

by  /  14 November 2016

Injecting stem cells into young rats makes them more social and flexible when learning tasks than before the treatment.

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December 2015
News

‘CRISPR’ way to cut genes speeds advances in autism

by  /  14 December 2015

A molecular Swiss army knife for DNA is hewing a path to clarify the subtle effects of thousands of autism-linked mutations.

1 Comment
October 2015
News

Environmental double hit may induce seizures, autism behaviors

by  /  21 October 2015

The combination of prenatal stress and a preterm labor drug may elicit seizures and autism-like behaviors in rat pups.

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News

Differences between rodents show limitations of models

by  /  20 October 2015

The same autism-linked mutation can lead to dramatically different behaviors in rats and mice.

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April 2015
Opinion

Blood pressure drug may protect brain from seizures

by  /  7 April 2015

A blood pressure drug called bumetanide may shield the brain from the effects of severe seizures early in life.

10 Comments
November 2014
News

Enriched environment staves off autism-like behavior in rats

by  /  20 November 2014

Rats exposed in utero to the epilepsy drug valproic acid, a risk factor for autism, do not develop autism-like behaviors if they are reared in a stimulating environment. Researchers presented the unpublished findings yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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News

Family of autism-linked proteins helps neurons communicate

by  /  16 November 2014

The SHANK family of proteins, some of which are strong autism candidates, work together to facilitate brain signaling, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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September 2014
Opinion / Viewpoint

Optimizing behavioral assays for mouse models of autism

by  /  23 September 2014

As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.

3 Comments
June 2014
News

For autism research, rats may be new top model

by  /  9 June 2014

Two new rat models of autism don’t roughhouse like normal rats do, and show some compulsive behaviors, according to a study published in April in Behavioral Neuroscience. The models underscore the advantage rats have over mice in modeling complex social behaviors. 

6 Comments