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Tag: PTEN

July 2020
DNA helix with mutation or deletion
News / Toolbox

Scores forecast effects of mutations in autism gene

by  /  8 July 2020

A new analysis links individual mutations in a gene called PTEN to a person’s odds of having autism, cancer or other conditions.

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May 2020
News

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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March 2020
microscopic views of proteins
News

Alzheimer’s protein turns up as potential target for autism treatments

by  /  2 March 2020

Lowering the levels of a protein called tau, best known for its involvement in Alzheimer’s disease, improves behavior in two mouse models of autism.

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February 2020
News

Large mutations may explain diverse outcomes from autism gene

by  /  24 February 2020

Deletions and duplications of long stretches of DNA may increase the likelihood of autism in people who have a mutation in a gene called PTEN.

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November 2019
News

Mouse study reveals overlooked target for autism therapies

by  /  20 November 2019

Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.

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Close-up of child's hand on wet window
News

Mutations in cancer gene tied to unique autism traits

by  /  14 November 2019

Autistic people who carry mutations in a gene called PTEN have distinct behavioral and motor problems.

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October 2019
News

Transplanted neurons rescue social behavior but not brain circuits

by  /  20 October 2019

Injecting cells called interneurons into the brains of a mouse model of autism restores typical social behavior. But the reason for this effect is a puzzle.

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News

Single molecule tracks with mutation’s path to autism, cancer

by  /  17 October 2019

A molecule made by mitochondria, the energy factories of cells, might help doctors forecast the impact of mutations in a top autism gene.

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July 2019
proteins up close
News

Study hints at dietary chemical as therapy for type of autism

by  /  1 July 2019

A compound derived from cruciferous vegetables, such as broccoli and kale, might limit the impact of certain mutations in an autism gene.

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May 2019
Computational Modeling of BRSK2 Missense Variants
News

Matchmaking site for genes leads scientists to autism candidate

by  /  6 May 2019

A website called GeneMatcher has helped researchers identify a new gene for intellectual disability, developmental delay and autism.

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