Skip to main content

Spectrum: Autism Research News

Tag: PTEN

December 2014

Method predicts impact of DNA variants on gene expression

by  /  18 December 2014

A new computational approach predicts how sequence variations in both the coding and noncoding regions of a gene affect the gene’s expression. The method, described today in Science, may help researchers understand how specific variants contribute to disorders such as autism.

Comments

Sequencing study clarifies impact of autism mutations

by  /  15 December 2014

Researchers are taking a second look at dozens of autism candidate genes, sequencing them in thousands of individuals to bolster the evidence linking them to autism.

Comments

Facial measurements resurface in search for autism clues

by  /  8 December 2014

A group of scientists is using fast, accurate and minimally invasive measurement systems to revive the once-tedious trade of dysmorphology, or the study of unusual facial features, in autism.

Comments
November 2014

Mystery gene uncovered in autism studies may steer neurons

by  /  26 November 2014

Comments

Genetics first: A fresh take on autism’s diversity

by  /  24 November 2014

Each child with autism is different from the next. One approach rapidly gaining momentum makes sense of this diversity by grouping children together based on their genetics, then looking for patterns in their symptoms. The long-term aim: personalized treatments for each subtype of autism.

Comments

Diabetes drug is sweet cure for fragile X in fruit flies

by  /  19 November 2014

The memory and sleep troubles that accompany fragile X syndrome originate in a glitch in insulin signaling, suggests an unpublished study of fruit flies presented today at the 2014 Society for Neuroscience annual meeting in Washington, D.C. The study points to a widely available diabetes treatment for the syndrome.

Comments

Autism-linked gene guides growth of subtype of neurons

by  /  19 November 2014

Mice missing PTEN, a strong autism candidate gene, in a subtype of inhibitory neurons in one part of the brain show signaling abnormalities and social deficits. Researchers presented the unpublished work yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

Comments
October 2014

Scientists catalog effects of PTEN mutations in autism

by  /  27 October 2014

People with autism who have mutations in a gene called PTEN have a distinct profile of cognitive impairments and structural abnormalities in the brain. The profile, published 7 October in Molecular Psychiatry, points to a subtype of autism with these features.

Comments

Seizures trigger autism-like behaviors in mice

by  /  23 October 2014

Mice with an extra copy of the autism-linked gene UBE3A show abnormal social behavior after experiencing recurrent seizures. The findings, presented Tuesday at the Autism Consortium Research Symposium in Boston, provide one possible explanation for why seizures and autism often go hand in hand.

Comments
April 2014

High-throughput screen finds genes that link neurons

by  /  30 April 2014

A new algorithm allows researchers to search among hundreds of genes and identify those involved in building synapses, the junctions that transmit signals between neurons, according to a report published 14 March in PLoS One.

Comments