SHANK1 — a member of a family of proteins linked to autism — does not cause autism-like social deficits when mutated in mice, according to a study published online in September in Brain Research.
Children with Williams syndrome are chatty, have rich vocabularies and love to tell stories. Yet they have trouble learning certain complex rules of grammar, according to a study published in the Journal of Speech, Language and Hearing Research.
People with autism show differences in the levels of various gene products compared with their unaffected siblings, according to a study published online in September in Brain Research.
A tumor suppressor best known for its role in colorectal cancer plays a critical role in forming connections between neurons, according to a study in the August 18 issue of the Journal of Neuroscience.
A new study, published in September in PLOS Genetics, shows the importance of comparing cases to controls when linking mutations to a disorder. The researchers propose a new method of analysis that takes into account the large size of many genes expressed in the brain.
The loss or delay of language is one of the most common — and most noticeable — features of autism.
“I don’t know anything about Williams syndrome”: That isn’t exactly how you’d expect a talk at a meeting on the syndrome to begin, but it happened more than once at a symposium on the disorder last week. Could scientific interchange between Williams syndrome and autism researchers benefit people with either condition?
Individuals with autism spend less time looking at eyes than at the mouth because they actively shift their gaze away from the eye region, according to a study published in September in the Journal of Neuroscience.
Chemicals produced by their mother’s immune system in utero alter the size of several key brain regions in people with schizophrenia, enlarging chambers that store cerebrospinal fluids, and shrinking parts of the cortex involved in processing emotion and memory.
A mouse model of Williams syndrome pinpoints a genetic region associated with the social behavior seen in the disorder, and may also yield insights into autism, says researcher Uta Francke, professor emeritus of genetics at Stanford University.