Small duplications in chromosomal region 16p11.2 increase the risk of schizophrenia about 14-fold, confirming the mutation’s importance in the disorder, according to a study published online 25 October in Nature Genetics.
Giving mouse models of Rett syndrome access to toys, wheels and contact with other mice rescues motor skill and other deficits characteristic of the disorder, according to results presented in a poster session Wednesday at the Society for Neuroscience meeting in Chicago.
Mice lacking a gene located in the chromosomal region 22q13 — which has been linked to autism — have motor learning and social deficits reminiscent of the disorder, according to unpublished findings presented in a poster session yesterday at the Society for Neuroscience meeting in Chicago.
Antibodies directed against the fetal brain are present in some mothers of children with autism, confirming previous findings and suggesting that the antibodies could be used as a marker for the disorder, according to unpublished research presented yesterday at the Society for Neuroscience meeting in Chicago.
Selectively disrupting an autism-related gene in cultured human neurons causes a dramatic imbalance of excitation and inhibition in cell signaling, according to unpublished results presented today at the Society for Neuroscience meeting in Chicago.
Deleting a neuronal protein associated with autism causes oxidative stress — characterized by an excess of free radicals — which has been linked to diseases such as diabetes and Alzheimer’s, according to new research in worms. The results were presented yesterday at a poster session at the Society for Neuroscience meeting in Chicago.
After a Monday afternoon poster session at the Society for Neuroscience meeting in Chicago, Noboru Hiroi talked about the challenges of following up human genetic findings in the mouse.
New pharmacological and behavioral interventions can reverse characteristics of autism in a mouse model of the disorder, according to unpublished results presented in poster sessions today at the Society for Neuroscience meeting.
Two variants in a gene needed for the cell’s energy balance may protect the carriers from autism, according to an unpublished study presented today at the Society for Neuroscience meeting in Chicago.
Mice missing FKBP12, a gene involved in a cancer pathway, show repetitive behavior and an impaired ability to socialize with other mice, and could be used to study autism, according to unpublished results presented at a poster session today at the Society for Neuroscience meeting.