Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

Advances in research and help from families have brought scientists to the brink of an effective therapy for Angelman syndrome.

Playing games designed to hone the ability to intuit others’ thoughts and feelings increases activity in regions of the social brain.

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

The American Academy of Pediatrics issued new guidelines yesterday upholding that central role of medications accompanied by behavioral therapy in ADHD treatment.

Experimental surgeries to prevent seizures may help scientists understand the link between autism and epilepsy.

Researcher Randi Hagerman is a big proponent of metformin — a diabetes drug that she is testing in people with fragile X syndrome. In fact, Hagerman takes the drug herself as a preventive measure against cancer.

A behavioral therapy called pivotal response treatment may boost the communication skills of autistic children with language delay better than do standard speech and autism therapies.

Researchers have created a microscopic particle that traps immune molecules found in a woman that are linked to autism in her child.