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Spectrum: Autism Research News

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Signs & Symptoms

Autism’s core symptoms accompany a constellation of subtle signs that scientists are just beginning to unmask.

October 2019
Heart surgery

Children with congenital heart defects have increased odds of autism

by  /  24 October 2019

Children who are born with mild heart problems are more likely to be autistic than their typical peers are.

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micrographs of brain areas in red.

Drug counteracts effects of doubled autism gene

by  /  24 October 2019

An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.

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Gene-edited marmosets may mimic Rett syndrome traits

by  /  23 October 2019

Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.

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UBE3A

Rat model mimics communication problems in Angelman syndrome

by  /  23 October 2019

Rats missing UBE3A, the gene mutated in people with Angelman syndrome, squeak frequently but tend not to be responsive to the play and squeaks of other rats.

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Monkey face with heatmap overlay

Monkey avatar may provide clues to face-processing problems in autism

by  /  22 October 2019

Researchers have created an animated monkey avatar that makes realistic facial expressions — and that may yield insight into how autistic people interpret facial expressions.

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Enlarged amygdala may forecast anxiety, depression in autistic children

by  /  22 October 2019

A tiny chunk of the brain’s emotion enter, the amygdala, is enlarged in some autistic children; the larger this piece, the more anxious and depressed the child is likely to be.

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Cesarean sections may leave young brains vulnerable to injury

by  /  22 October 2019

Delivery by cesarean section leads to subtle brain and behavioral alterations in mice, particularly those delivered prematurely.

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a human brain model made of springs is shaking on its spring base

The link between epilepsy and autism, explained

by  /  21 October 2019

Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?

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What Ehlers-Danlos syndrome can teach us about autism

by  /  21 October 2019

Not much is known about the connection between autism and Ehlers-Danlos syndrome, a condition that affects collagen. But preliminary work provides tantalizing clues.

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Mouse shows friendliness to all mice, friends or strangers

What two rare ‘social’ syndromes reveal about autism

by  /  21 October 2019

Studying Smith-Magenis and Potocki-Lupski syndromes — two single-gene conditions in which people have trouble reading social cues — may boost our understanding of autism.

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