Sleep problems may contribute to or derive from autism traits — or both. After decades of work, researchers are beginning to uncover the biological connections between the two conditions, revealing new paths to potential treatments.

The Rett Syndrome Global Registry is gathering data from people around the world with the rare condition to support clinical trials.

The current system to approve genetic and metabolic conditions for newborn screening can’t keep pace with research on new therapies. Don Bailey wants to bring it up to speed.

A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.

Oxytocin, cemented in the popular imagination as the “love molecule,” could serve as a treatment for some autistic people who naturally have low levels of the hormone, researchers say.

The investigational drug arbaclofen makes autistic people’s brains respond to a visual task more like non-autistic people’s brains do.

Motor differences are more relevant than has historically been appreciated for understanding, assessing and supporting people on the spectrum.

How chemical tags called methyl groups position themselves on genetic sequences may hint at some of the causes of autism.

Deleting a copy of the gene TBX1 depletes the fatty myelin insulation that surrounds neurons and reduces cognitive speed in mice.

In this edition of Null and Noteworthy, the Interagency Autism Coordinating Committee grapples with “groundbreaking” research and two reviews of interventions come to conflicting conclusions.