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Tag: treatments

July 2021
Micrographs comparing motor cortex neurons in mice with and without an extra copy of MECP2 gene.
News

Blocking key pathway reverses brain, behavior changes in autism mouse model

by  /  19 July 2021

Neurons in mice with an autism-linked mutation sprout extraneous protrusions, an overgrowth accompanied by above-average motor learning. Inhibiting a cell signaling pathway reverses the effect.

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Illustration shows yellow landscape with blue sections and a lot of trains on paths with kids on the trains, going different directions.
Features / Deep Dive

Mapping the futures of autistic children

by  /  14 July 2021

Researchers can roughly project what autistic children’s lives will look like years down the road. But how good is their crystal ball — and what are its benefits?

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News

Polypharmacy, shifting prescriptions common for autism comorbidities

by  /  1 July 2021

Roughly 30 percent of people with autism plus another condition, such as anxiety, are prescribed three or more psychotropic medicines. And that mix frequently changes from year to year.

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June 2021
Dr. Huda Zoghbi portrait
News / Profiles

Huda Zoghbi: Taking genetic inquiry to the next level

by  /  25 June 2021

Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.

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Illustration of transporter mice in brain maze
News

After 60 years, scientists are still trying to crack a mysterious serotonin-autism link

by  /  4 June 2021

The high levels of serotonin seen in the blood of some autistic people have confounded scientists for more than half a century. Despite so little progress, some researchers refuse to give up.

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May 2021
News

Stimulant restores cell signaling, eases behavior issues in animals missing autism gene

by  /  28 May 2021

Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.

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Dr. Elizabeth Berry-Kravis stretching during a run.
News / Profiles

Elizabeth Berry-Kravis: Running a marathon for fragile X syndrome

by  /  26 May 2021

Elizabeth Berry-Kravis has spent decades uncovering molecular clues to fragile X syndrome and crafting trials of treatments. Her efforts are paying off.

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News / Toolbox

New benchmark for autism scale may help gauge therapies

by  /  18 May 2021

Researchers have defined a change in score on a popular autism rating scale that signifies a meaningful improvement in core traits. The measure could help scientists assess the effectiveness of autism treatments in clinical trials.

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Visual stimulus of 4 circles with black and white stripes.
News

Visual task flags autistic people who respond to GABA agonists

by  /  14 May 2021

The investigational drug arbaclofen makes autistic people’s brains respond to a visual task more like non-autistic people’s brains do.

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Child's hands playing on a white table with blue sand.
News

Methodological issues plague studies of early autism interventions

by  /  6 May 2021

Multiple types of bias and an overreliance on caregiver reports have clouded research on the effectiveness of early interventions for autism for nearly three decades.

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