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Spectrum: Autism Research News

Tag: treatments

July 2023
Illustration of half of a brain on the left and half of a heart on the right

Change of heart and mind: Autism’s ties to cardiac defects

by  /  21 July 2023

Children with congenital heart disease have an increased likelihood of autism. Why?

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Prenatal exposures; Angelman trial suspension; autistic adult well-being

by  /  17 July 2023

This month’s issue of the Null and Noteworthy newsletter breaks down some negative results involving prenatal exposures, an experimental treatment for Angelman syndrome, and the role that age at autism diagnosis plays in subsequent outcomes, and more.

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Unknown isoform adds twist to theory of fragile X origins

by  /  11 July 2023

Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.

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June 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Gene therapy for Rett; return to arbaclofen

by  /  29 June 2023

This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.

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Research image of gene-edited mouse liver cells compared to controls.

Latest ‘prime-editing’ tools tackle delivery, safety issues

by  /  27 June 2023

The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.

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Portrait of Connie Kasari.

Social communication and developmental disorders with Connie Kasari

by  /  1 June 2023

In this episode of “Synaptic,” Kasari talks about the need for inclusion in educating autistic children, what drew her into the autism research field, and growing up on the family farm.

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May 2023
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring

by  /  30 May 2023

This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

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Composite research image of organoids at several stages of development.

Genetic background sways effects of autism-linked mutation

by  /  18 May 2023

Experiments offer clues to why certain mutations are associated with autism in some people and not others.

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A father and son play with a wooden toy horse on the floor.

Autism intervention before age 2 may aid social, language skills

by  /  16 May 2023

Autistic toddlers who receive a personalized intervention at about 18 months of age gain more abilities than those who start the therapy nine months later.

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Photograph of white pills and blister pack on blue pastel colored background.

Trials of arbaclofen for autism yield mixed results

by  /  5 May 2023

Autistic children taking the drug showed improvements in some behaviors but not in their social skills.

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