After the vasopressin antagonist balovaptan flopped in a late-stage clinical trial, Suma Jacob and her colleagues took stock of all the factors that might have complicated the results.

Doctors can prescribe it, but evidence that ketamine eases autism traits is still preliminary.

Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.

ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.

Strategies to replace or compensate for mutated copies of the TCF4 gene could lead to treatments for this profound form of autism, a new study suggests.

Drugs such as LSD act primarily on the serotonin system, which is implicated in autism — and some autistic people who experiment with psychoactive compounds report enhanced social connections, among other benefits. But researchers have more questions than answers.

The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.

Early interventions for autism lack solid data. The source of this problem is murky but may stem from ongoing debates about evidence quality and entrenched conflicts of interest within the field.

The ability to conduct large-scale screening in human neurons could accelerate the discovery of autism treatments.

The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.