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Spectrum: Autism Research News

Tag: mouse models

November 2014

Simple steps aim to solve science’s ‘reproducibility problem’

by  /  17 November 2014

Leaders from the National Institutes of Health and Nature Publishing Group say an array of simple reforms can boost the reliability of research findings. Their suggestions spurred a lively audience discussion yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Targeting potassium channel eases autism symptoms in mice

by  /  17 November 2014

Lowering the levels of a certain ion channel reverses autism-like behaviors in a mouse model of fragile X syndrome, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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New ‘hands-free’ device controls mouse movements

by  /  17 November 2014

With a tiny diode inserted into a mouse’s skull, researchers can stimulate its neurons while it runs freely on an exercise wheel or crawls through cardboard tubes, they reported yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Songs, squeaks combine to tell story about human language

by  /  17 November 2014

Birdsong is a valuable tool for studying language, and mice are the models of choice for genetic manipulation of behavior. Together, birds and mice can yield unparalleled insights into human language, suggests unpublished research presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Non-starring cells may be key in fragile X syndrome

by  /  17 November 2014

Mice missing the FMR1 gene only in star-shaped brain cells called astrocytes recapitulate key features of fragile X syndrome. Researchers presented the unpublished results today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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The next hot topic in autism research? Immune cells

by  /  16 November 2014

Some cases of autism may result from glitches in immune cells in the blood: This provocative idea stems from a series of unpublished mouse studies presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Questions for Karen Parker: Probing monkey social behavior

by  /  4 November 2014

Like people, monkeys vary widely in their social abilities. Behavioral neuroscientist Karen Parker explains how studying social behavior in monkeys can advance how we understand and treat autism.

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October 2014

Seizures trigger autism-like behaviors in mice

by  /  23 October 2014

Mice with an extra copy of the autism-linked gene UBE3A show abnormal social behavior after experiencing recurrent seizures. The findings, presented Tuesday at the Autism Consortium Research Symposium in Boston, provide one possible explanation for why seizures and autism often go hand in hand.

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Analysis of mouse brains maps subgroups of autism

by  /  13 October 2014

A brain imaging study of 26 mouse models of autism reveals a broad range of structural abnormalities. The models cluster into groups with similar features, reports a study published 9 September in Molecular Psychiatry.

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Database details neural gene interactions in developing mice

by  /  8 October 2014

A new online resource called MouseID Genes stores information about gene interactions in the developing mouse brain and spinal cord.

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