Mouse models
‘It must be something I ate’ is hard-wired into the brain
Feeling sick reactivates “novel flavor” neurons, according to a new study in mice, and points to a dedicated circuit for learning to avoid unsafe food.
‘It must be something I ate’ is hard-wired into the brain
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Microglial overreaction to atypical neurons may drive autism
Alzheimer’s scientist to correct two papers because of data inconsistencies
Anonymous commenters raised concerns about the statistical methods that Soyon Hong and her colleagues used in their work.
Alzheimer’s scientist to correct two papers because of data inconsistencies
Newly found hypothalamus circuits shape bullying behaviors in mice
Activity in the tiny brain region helps submissive rodents learn to avoid aggressors, and aggressive mice to curb their attacks, according to two recent studies.
Newly found hypothalamus circuits shape bullying behaviors in mice
Synaptic protein’s shape-shifting skills propel plasticity
SYNGAP supports learning without tapping its eponymous “GAP” enzymatic activity, according to a new study.
Synaptic protein’s shape-shifting skills propel plasticity
Monkey studies throw wrench into decade-old idea about movement’s effect on visual cortex
Movements that boost activity in the visual cortex of mice have the opposite or no effect in marmosets and macaques, prompting questions about whether mice are a suitable model for the primate visual system.
Monkey studies throw wrench into decade-old idea about movement’s effect on visual cortex
Being uncomfortable and PKMzeta with André Fenton
The director of the Center for Neural Science shares a ghost story and talks about his collaboration with Todd Sacktor.
Being uncomfortable and PKMzeta with André Fenton
Sheena Josselyn and memories lost, found and created
Her hunt for the engram opened a new avenue in memory research.
Sheena Josselyn and memories lost, found and created
Noisy brain may underlie some of autism’s sensory features
Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.
Noisy brain may underlie some of autism’s sensory features
Immune-activation model mice escape infantile amnesia, retain early memories
Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.
Immune-activation model mice escape infantile amnesia, retain early memories
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Neuroscience needs a research-video archive
Video data are enormously useful and growing rapidly, but the field lacks a searchable, shareable way to store them.
Neuroscience needs a research-video archive
Video data are enormously useful and growing rapidly, but the field lacks a searchable, shareable way to store them.
Inclusivity committee disbands in protest at Canadian neuroscience institute
The majority of an 11-person committee resigned from the group this week following news that a staff position overseeing equity, diversity and inclusion would not be renewed.
Inclusivity committee disbands in protest at Canadian neuroscience institute
The majority of an 11-person committee resigned from the group this week following news that a staff position overseeing equity, diversity and inclusion would not be renewed.
How to explore your scientific values and develop a vision for your field
As a new professor, I was caught off guard by one part of the job: my role as an evaluator.
How to explore your scientific values and develop a vision for your field
As a new professor, I was caught off guard by one part of the job: my role as an evaluator.