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Spectrum: Autism Research News

Tag: intellectual disability

May 2018

Intellectual disability’s introduction in the DSM-5: What’s the impact?

by  /  9 May 2018

The move to replace ‘mental retardation’ with ‘intellectual disability’ is widely accepted, but little data exist on the impact of this change.


Why the definition of autism needs to be refined

by  /  9 May 2018

Five years after its latest revision, the manual used to diagnose autism is back under scrutiny, as evidence suggests it excludes some people on the spectrum.

April 2018
Scan of the frontal lobe of the brain

Autism syndrome involves constellation of medical issues

by  /  30 April 2018

Mutations in a gene called ADNP lead to a syndrome that includes autism, intellectual disability and problems with the gut, eyesight, heart and brain.

boy playing with a fidget spinner

Co-occurring conditions alter timing of autism diagnosis

by  /  23 April 2018

Children with autism typically have four or five other conditions, such as attention deficit hyperactivity disorder, that can affect when they are diagnosed.

March 2018
Neurons from mice missing OTUD7A (right) have fewer spines than do those from controls (left).

Studies pinpoint key gene in region linked to autism

by  /  21 March 2018

A single gene, OTUD7A, may account for most of the features seen in people missing a segment of chromosome 15 known as 15q13.3.

two people walking down dirt road in a town in colubmia

‘Founder effect’ may have fueled fragile X cluster in Colombian town

by  /  19 March 2018

A semirural Colombian town called Ricaurte is home to the largest recorded genetic cluster of people with mutations linked to fragile X syndrome.

child looking out a hospital window

Low intelligence, repetitive actions tied to self-injury in autism

by  /  7 March 2018

People with autism who are admitted to the hospital for self-injury tend to have low intelligence quotients and severe repetitive behaviors.

February 2018
child walking on stone path with parents' help

Genetics underscores importance of motor deficits in autism

by  /  28 February 2018

Spontaneous mutations that impair proteins may lead to motor problems in children with autism.

Newly flagged genes for developmental conditions (triangles) cluster in networks with previously identified risk factors (circles).

New software mines data for autism risk genes

by  /  16 February 2018

An algorithm combs through genetic data to identify variants involved in autism and four other brain conditions.

January 2018
illustration of DNA strand

Variant analysis may vastly underestimate heritability of autism behaviors

by  /  29 January 2018

Existing genome scans do not detect many of the DNA variants that underlie behavioral problems.