Families of children with mutations in a gene called SYNGAP1 have spurred research into the effects of the mutations on people — and how to treat them.

The lack of people with intellectual disability in studies of autism has a profound effect on our understanding of the condition.

A website called GeneMatcher has helped researchers identify a new gene for intellectual disability, developmental delay and autism.

Children in families with a history of brain conditions may be at increased odds of being autistic.

Without timely intervention, intellectual disability in autistic children can worsen as they grow older.

Autism may be just as common among children missing a segment of chromosome 16 as it is in those with an extra copy.

Two independent sets of mice missing a copy of SETD5, a top autism gene, link the gene to the condition’s traits.

Many countries in Europe are reckoning with the growing demand for genetic tests for autistic people — and the accompanying ethical and scientific considerations.

Some children who dramatically lose a range of abilities after age 2 may have a condition called childhood disintegrative disorder.

A new advocacy group for people with severe autism taps into the deep divide in the community over who should speak for those on the spectrum.