Activating the expression of FMR1, the gene mutated in fragile X syndrome, in adult mice reverses symptoms of the syndrome, according to a poster presented Monday at the Society for Neuroscience annual meeting in New Orleans.
Trouble with theory of mind, or the ability to infer what other people think or believe, is one of the most well-known deficits in autism. Two new studies show that theory of mind is also lacking in people with autism-related syndromes.
A cholesterol-lowering drug called lovastatin prevents seizures in mice that model fragile X syndrome, according to a poster presented Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.
Rats lacking FMR1, the gene mutated in people with fragile X syndrome, do not learn to discriminate between human speech sounds like control rats do, according to research presented Monday evening at the 2012 Society for Neuroscience annual meeting in New Orleans.
A research colony of feral monkeys may help scientists study how genetics contributes to complex social behaviors in fragile X syndrome, according to unpublished research presented Monday at the 2012 Society for Neuroscience annual meeting in New Orleans.
Rapid progress in gene discovery and an emerging map of the molecular landscape of normal brain development are presenting unprecedented opportunities to unravel the biology of autism spectrum disorders, say Matthew State and Nenad Sestan.
Researchers are testing a wealth of new treatments for fragile X syndrome, an inherited intellectual disability often accompanied by autism. They presented preliminary results from animal studies of several drugs, as well as an automated approach for screening compounds, Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.
Astrocytes, star-shaped brain cells that support neurons, may be needed for mice to learn motor skills, according to unpublished research presented Saturday at the 2012 Society for Neuroscience annual meeting in New Orleans.
Deleting an enzyme that regulates protein synthesis reverses some of the molecular and behavioral deficits in a mouse model of fragile X syndrome, according to research published 2 October in Neuron.
Deleting CYFIP1, a gene within a region linked to Angelman syndrome and autism, in mice leads to symptoms reminiscent of fragile X syndrome, according to a study published 10 August in PLoS One.