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Tag: Drosophila

July 2015

Dispatches from the 2015 Dup15q Alliance Scientific Meeting

by  /  30 July 2015

These short reports from our reporter, Nicholette Zeliadt, give you the inside scoop on developments at the 2015 Dup15q Alliance Scientific Meeting.

March 2015

Treatment eases fragile X symptoms in flies, mice

by  /  9 March 2015

Blocking an enzyme involved in learning and memory corrects brain abnormalities and improves memory in fly and mouse models of fragile X syndrome.

February 2015
News / Toolbox

Method lights up brain activity in living animals

by  /  18 February 2015

A new microscopy technique creates colorful three-dimensional images of brain activity in awake mice.

November 2014

Diverse dopamine defects found in people with autism

by  /  19 November 2014

Experimental drugs can reverse the effects of some autism-linked mutations in the dopamine transporter, a protein that shuttles the chemical messenger dopamine into neurons. Researchers presented the unpublished findings in five posters yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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May 2014
News / Toolbox

Brain-wide map links fruit fly behaviors to neurons

by  /  21 May 2014

Triggering neuron activity with flashes of light allows scientists to tie behaviors in fruit fly larvae to specific neuron groups, reports a study published 25 April in Science. The study catalogs the associations between neurons and the movements they control.

March 2014
Opinion / Viewpoint

Emerging importance of chromatin in autism risk

by ,  /  18 March 2014

Sequencing studies over the past few years have made a dramatic and unexpected discovery: Many of the mutations in individuals with autism are in genes that regulate chromatin, which helps package DNA in the cell nucleus, say Gerald Crabtree and Aryaman Shalizi.

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News / Toolbox

New molecules help researchers orchestrate brain activity

by  /  12 March 2014

Using newly discovered molecules from algae, researchers can control the activity of two families of neurons in a single mouse or fly, they reported 9 February in Nature Methods.

November 2013

Genetics: Spontaneous mutation links dopamine to autism

by  /  12 November 2013

A newly discovered spontaneous mutation, described 27 August in Molecular Psychiatry, links autism to changes in the regulation of the chemical messenger dopamine.

September 2013

In autism-related disorders, RNA turns out to be key

by  /  26 September 2013

An enzyme that may keep RNA tangle-free as it’s translated into protein is missing in some people with schizophrenia and learning difficulties. The enzyme also cooperates with the protein missing in fragile X syndrome to bind RNA, suggesting a role in protein synthesis. That’s the upshot from two studies published in the September Nature Neuroscience.

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August 2013

Molecular mechanisms: Rett, Angelman genes work together

by  /  13 August 2013

The genes involved in Rett and Angelman syndromes may collaborate to regulate the expression of other proteins, according to a study published 19 July in Biochemical and Biophysical Research Communications. This may explain the overlap in symptoms between the two disorders, the researchers say.