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Spectrum: Autism Research News

Tag: cortex

January 2015

Method charts lifetime expression of DNA in brain

by  /  21 January 2015

A new database that maps changes in gene expression in the prefrontal cortex shows that autism-linked genes are expressed differently than other genes through six stages of life.

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Head movement in scanners skews brain measurements

by  /  9 January 2015

Even small movements of the head during magnetic resonance imaging can lead to spurious measurements of brain structures, according to a new study.

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December 2014

Notable papers of 2014

by  /  22 December 2014

It’s no easy feat to whittle down the list of the most influential autism papers to a mere 10. So please consider this but a taste of the burgeoning field, presented in chronological order and based on suggestions from many researchers.

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Postmortem brains point to molecular signature of autism

by  /  22 December 2014

An analysis of genes expressed in the postmortem brains of people with autism has identified three molecular pathways linked to the disorder. The findings, published 10 December in Nature Communications, add to mounting evidence that the myriad causes of autism converge on common biological processes.

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Method isolates protein complexes from neuronal junctions

by  /  17 December 2014

Researchers have for the first time isolated and characterized protein complexes found at the points of connection between neurons. Mutations in some of these proteins are linked to autism.

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Brains of people with autism show altered growth with age

by  /  11 December 2014

Several brain regions in people with autism become enlarged earlier than usual during childhood and shrink too soon during adulthood, finds an eight-year imaging study.

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‘Brain-normalizing’ therapy points to new kind of biomarker

by  /  1 December 2014

Pivotal response treatment, an effective form of behavioral therapy for autism, normalizes brain activity in children with the disorder, according to a small study published earlier this month in Brain Imaging and Behavior. This suggests that brain imaging can signal early responses to autism treatments.

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November 2014

In autism, RNA snippets vary little by brain region, age

by  /  20 November 2014

The expression patterns of microRNAs vary less by brain region and age in people with autism than in controls. Researchers presented the unpublished findings Tuesday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Calcium sensor leaves permanent mark in activated neurons

by  /  17 November 2014

Researchers have engineered a fluorescent sensor that irreversibly switches from green to red when a neuron fires, thereby serving as a permanent mark of neuronal activation. They described the unpublished work Monday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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Songs, squeaks combine to tell story about human language

by  /  17 November 2014

Birdsong is a valuable tool for studying language, and mice are the models of choice for genetic manipulation of behavior. Together, birds and mice can yield unparalleled insights into human language, suggests unpublished research presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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