This year’s top papers deepen our understanding of autism’s genetics and reveal mixed results from trials of autism therapies.

No diet is likely to treat autistic people on a large scale, but diets based on a genetic profile may bring big benefits to a few.

Understanding how gaze differs in autistic people may help improve their lives.

The United Kingdom’s exit from the European Union would endanger continent-wide collaborations.

Special diets that eliminate certain foods or contain added supplements have minimal impact on autism traits, according to a review of 27 clinical trials.

Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.

Khara Ramos explains how the Brain Initiative incorporates the emerging field of ‘neuroethics’ into the research it funds.

Canada’s health department is now sharing study results on new drugs and treatments online. Transparency advocates want the United States to do the same.

Tuberous sclerosis provides a unique opportunity to understand autism because about half of people with that single-gene condition also have autism.

Experimental surgeries to prevent seizures may help scientists understand the link between autism and epilepsy.