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Tag: clinical trials

December 2020
researcher facing off with the coronavirus.
Features / Special Reports / Hindsight is 2020: The year in review

Rewind: Spectrum’s best from 2020

23 December 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

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Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome
Features / Special Reports / Hindsight is 2020: The year in review

Hot topics in autism research, 2020

23 December 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

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November 2020
Young boy looking upset, sits on couch with crossed arms.
Opinion / Viewpoint

Errors of omission: Why we are deeply concerned about research on autism therapies

by , , ,  /  24 November 2020

Studies of autism treatments rarely report adverse events, and the scientists involved often fail to disclose their conflicts of interest.

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Photograph of lab researchers at Ultragenyx
News

Gene therapy trial for autism-linked condition is put on hold

by  /  5 November 2020

All five participants in a clinical trial of a gene therapy for Angelman syndrome experienced leg weakness, leading sponsors to pause the study.

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October 2020
Ralf Schmid, the research director in Neurodevelopmental diseases at the Gene Therapy Program Orphan Disease Center, loads replicated mouse dna into wells in the gel before applying electric current to test the viability of the dna.
Features / Deep Dive

A quest for Quincy: Gene therapies come of age for some forms of autism

by ,  /  14 October 2020

A gene therapy for Angelman syndrome stands at the forefront of efforts to treat autism-linked conditions that stem from single genes.

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September 2020
Illustration of a neuron on top of a marijuana leaf surrounded by psychadelic colors.
News

Cannabis and autism, explained

by  /  7 September 2020

Autistic people and their families are increasingly experimenting with marijuana to try to ease problems such as insomnia, epilepsy and chronic pain — and traits of autism. But there is little evidence for its safety or effectiveness.

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Liquid medicine being poured from bottle onto spoon.
News

Bumetanide may benefit only a subset of autistic children

by  /  3 September 2020

Contrary to previous results, the blood pressure drug did not uniformly improve autism traits in a new clinical trial.

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July 2020
Man working from home office.
News

INSAR 2020, from home

by  /  31 July 2020

Like so many other events this year, autism’s biggest annual conference — the International Society for Autism Research meeting — was forced to go virtual because of the coronavirus pandemic.

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June 2020
News

Study finds little evidence to back cord-blood therapy for autism

by  /  11 June 2020

An infusion of umbilical cord blood does not improve social skills in autistic children, according to results from the largest, most rigorous test of the therapy for autism to date.

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April 2020
News

U.S. funding agency offers researchers flexibility during pandemic

by  /  7 April 2020

The National Institutes of Health is offering autism researchers who are coping with the coronavirus pandemic flexibility with their grant applications, budgets and progress reports.

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