The brains of mice carrying different mutations in the autism-linked gene TBR1 display different molecular changes yet similar structural changes, resembling those previously found in autistic people with TBR1 mutations.
A new longitudinal study paints a favorable picture of the outcomes for many autistic adults in the city of Yokohama.
The ‘projectome’ charts axonal pathways between individual cells in the prefrontal cortex, a brain region implicated in autism.
The calcium-sensing instrument translates neuronal activity into signals that can be detected via functional magnetic resonance imaging (fMRI).
The ability to conduct large-scale screening in human neurons could accelerate the discovery of autism treatments.
The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.
A modified version of a probe commonly used in animals detected neuronal activity across different cortical layers in three people undergoing brain surgery.
By automatically quantifying gait and posture in videos of mice, a new machine-learning tool could accelerate research on how autism-linked mutations or drug treatments affect motor skills.
A new viral variant can deliver genes exclusively to the brain, overcoming a key hurdle in treating neurological conditions using gene therapy.
Mice that express a fluorescent synaptic receptor reveal the interactions between neurons in unprecedented detail.