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Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

January 2021
Pills spilling out of falling prescription bottle.
News

Spectrum reporting prompts new review of common drug

by  /  29 January 2021

Aripiprazole, an antipsychotic medication marketed as Abilify, eases aggressive behavior in autistic children, but questions remain about its side effects.

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News / Toolbox

Method may improve safety of gene therapies targeting the brain

by  /  28 January 2021

A new approach for delivering gene therapy to the brain reduces nerve damage in primates and could help make gene therapies for conditions related to autism safer.

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News

New gene therapy methods deliver promise

by  /  14 January 2021

Two unpublished studies detail improved techniques for delivering gene therapies to the brain.

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Two mice in a rotarod machine
News

Mouse study sounds note of caution for Rett syndrome therapies

by  /  13 January 2021

Treatments for Rett syndrome that aim to boost levels of the protein MECP2 may not help everyone with the condition.

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two mice interacting.
News

Mice show brain, behavior changes weeks after oxytocin treatment

by  /  11 January 2021

Intranasal oxytocin may spur new neuron growth and changes in social behavior after a few weeks.

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December 2020
researcher facing off with the coronavirus.
Features / Special Reports / Hindsight is 2020: The year in review

Rewind: Spectrum’s best from 2020

23 December 2020

Our staff picks the stories, podcasts and special reports that stood out from the rest this past year.

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Micrograph of nerve cells being targeted by CRISPR enzyme to activate the silenced gene in Angelman syndrome
Features / Special Reports / Hindsight is 2020: The year in review

Hot topics in autism research, 2020

23 December 2020

The Spectrum team highlights five topics that distinguished autism research in 2020: diversity in data, gene therapies, subtyping, social circuitry and the ‘autism gene’ debate.

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White lab mouse sitting in a gloved hand.
Features / Special Reports / Hindsight is 2020: The year in review

Notable papers in autism research, 2020

23 December 2020

Gene therapies and the factors influencing autism traits top Spectrum’s list of the 10 most notable research findings we covered in 2020.

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Protein in brain
News

Drug helps mice with autism-linked mutation recognize others

by  /  21 December 2020

Mice that model 22q11.2 deletion syndrome lack social memory, but that trait can be reversed using a drug that targets the flow of potassium ions in neurons.

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November 2020
Owen leaving his home for a bike ride, followed by his therapists and teachers.
Features / Deep Dive

Owen’s odyssey: A year and a half after an autism diagnosis

by  /  25 November 2020

This is part 2 of Owen’s story. It tracks his early progress in treatment for autism. Part 1 described his difficult path to a diagnosis.

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