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Spectrum: Autism Research News

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Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

June 2023
A dentist examines a young girl’s teeth.

Easing sensory sensitivities in the clinic: Q&A with Leah Stein Duker

by  /  30 June 2023

Dentist or doctor visits can overwhelm autistic children with sensory sensitivities. Occupational therapy can help, Stein Duker says.

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Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Gene therapy for Rett; return to arbaclofen

by  /  29 June 2023

This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.

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Research image of gene-edited mouse liver cells compared to controls.

Latest ‘prime-editing’ tools tackle delivery, safety issues

by  /  27 June 2023

The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.

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A photograph of a mouse against a swirly, multi-colored backdrop

Psychedelics give mice second chance to learn social rewards

by  /  23 June 2023

The drugs may reopen a critical window during development in which the brain can more easily adjust its connections.

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Still from research video of mice socializing.

Multi-lab study hints at benefits of long-tested autism drug

by  /  8 June 2023

The results lend support for clinical trials of arbaclofen in people with an autism-linked condition, the researchers say.

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A researcher works with a young child.

Two scientists, two interventions: A ‘gentle rivalry’ to aid autistic children

by  /  2 June 2023

Minimally verbal autistic preschoolers gained new words and phrases in a head-to-head comparison of two interventions.

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Portrait of Connie Kasari.

Social communication and developmental disorders with Connie Kasari

by  /  1 June 2023

In this episode of “Synaptic,” Kasari talks about the need for inclusion in educating autistic children, what drew her into the autism research field, and growing up on the family farm.

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May 2023
Collage of multiple figures on a hillside looking at a large blue book in the distance.

Debate remains over changes in DSM-5 a decade on

by  /  31 May 2023

Changes to the DSM-5’s diagnostic criteria for autism were meant to add clarity, but they also generated new questions.

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A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring

by  /  30 May 2023

This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

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Jeremy Veenstra-VanderWeele looks directly into the camera with a calm expression in a close up shot.

Swings and misses with Jeremy Veenstra-VanderWeele

by  /  30 May 2023

A careful clinician who prizes evidence, Jeremy Veenstra-VanderWeele is happy to embrace trial failures, as long as he learns from them.

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