TOPIC

Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

December 2019
A single ecstasy pill on a blue background.
News

Distinct brain pathway underlies ecstasy’s social effects

by  /  11 December 2019

The drug popularly known as ecstasy may boost sociability through brain circuits distinct from that underlying its ‘high.’

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November 2019
Features / Deep Dive

Rethinking repetitive behaviors in autism

by  /  25 November 2019

Autistic people have long maintained that repetitive behaviors are beneficial. Emerging evidence in support of this idea is shaping new therapies.

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News

Drug combination mutes sensitivity to noise in autism mice

by  /  25 November 2019

A mix of two drugs eases hypersensitivity to noise in mice missing an autism gene — offering the promise of a similar treatment for autistic people.

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News

Mouse study reveals overlooked target for autism therapies

by  /  20 November 2019

Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.

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Portrait of Geraldine Bliss and her son Charles
Opinion / Q&A

New family group pursues treatments for autism-linked syndrome

by  /  19 November 2019

After a decade of working with the Phelan-McDermid Syndrome Foundation, Geraldine Bliss has co-founded a new organization to develop therapies for the condition.

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October 2019
Choosing between two plates: on the left, salmon and on the right, supplements.
News

Analysis finds little evidence to support dietary interventions for autism

by  /  28 October 2019

Special diets that eliminate certain foods or contain added supplements have minimal impact on autism traits, according to a review of 27 clinical trials.

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micrographs of brain areas in red.
News

Drug counteracts effects of doubled autism gene

by  /  24 October 2019

An experimental drug tamps down the expression of a gene duplicated in an autism-related condition and restores typical behavior in mice.

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Marijuana plant
News

Cannabis compound improves sociability in autism mouse model

by  /  22 October 2019

A single dose of cannabidiol, a component of marijuana, eases seizures and improves learning and sociability in mice with mutations in an autism gene called CDKL5.

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News

Mouse study hints at why fragile X drugs fail in trials

by  /  22 October 2019

Drug after drug has failed in clinical trials for fragile X syndrome. A new study provides an explanation — a decrease in the drugs’ effectiveness over time — and points to a new strategy that could circumvent this problem.

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linked hands in a pattern intertwined with DNA showing some broken parts, symbolizing mutations
News

Rett syndrome’s link to autism, explained

by  /  21 October 2019

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

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