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Spectrum: Autism Research News

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Treatments

Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.

May 2023
A patient fills out a form in a doctor's office waiting room

Medicaid waivers curb disenrollment among autistic young adults

by  /  26 May 2023

Autistic people tend to drop out of Medicaid once they reach adulthood in states that don’t waive the income restrictions on enrollment.

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Research image of oligodendrocytes in mice treated with clemastine compared to untreated mice.

Antihistamine aids myelination in Pitt-Hopkins mice

by  /  25 May 2023

The drug clemastine and other compounds that fortify the protective sheath around neurons may prove therapeutic for some genetic neurodevelopmental conditions.

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Composite research image of organoids at several stages of development.

Genetic background sways effects of autism-linked mutation

by  /  18 May 2023

Experiments offer clues to why certain mutations are associated with autism in some people and not others.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Arbaclofen results; another oxytocin edition

by  /  17 May 2023

New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.

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A father and son play with a wooden toy horse on the floor.

Autism intervention before age 2 may aid social, language skills

by  /  16 May 2023

Autistic toddlers who receive a personalized intervention at about 18 months of age gain more abilities than those who start the therapy nine months later.

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Research image of neurons and astrocytes.

Astrocytes fuel erratic firing in fragile X neurons

by  /  10 May 2023

A shift in astrocyte secretions may explain the atypical firing patterns of neurons derived from people with fragile X syndrome.

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Photograph of white pills and blister pack on blue pastel colored background.

Trials of arbaclofen for autism yield mixed results

by  /  5 May 2023

Autistic children taking the drug showed improvements in some behaviors but not in their social skills.

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April 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Serotonin drug; psilocybin phase 2; placebo response data

by  /  28 April 2023

This month’s issue of the Going on Trial newsletter explores why it’s more fun to have a beer with friends than by yourself — and how that informs an ongoing clinical trial for autism.

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An illustration of a scientist on a stage with a giant pill bottle that has been chopped in half.

Company on brink takes psilocybin to trial for fragile X syndrome

by  /  25 April 2023

The phase 2A trial has its detractors despite positive animal results and is being sponsored by a company that is struggling financially.

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Illustration of a room with DNA sequence wallpaper and three doors leading to abstract new environments.

The future of autism therapies: A conversation with Lilia Iakoucheva and Derek Hong

by  /  14 April 2023

If a therapy for autism’s core traits makes it to market, it will likely take one of three forms, the researchers say.

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