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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

October 2012

Anxiety drug enhances brain connections in autism

by  /  14 October 2012

A small pilot study suggests that the drug propranolol, typically used to treat hypertension and anxiety, enhances functional connectivity between brain regions and improves verbal fluency, according to research presented Saturday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Researchers reveal first brain study of Temple Grandin

by  /  14 October 2012

Temple Grandin, perhaps the world’s most famous person with autism, has exceptional nonverbal intelligence and spatial memory, and her brain has a host of structural and functional differences compared with the brains of controls, according to a presentation Saturday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Astrocytes may play starring role in learning

by  /  14 October 2012

Astrocytes, star-shaped brain cells that support neurons, may be needed for mice to learn motor skills, according to unpublished research presented Saturday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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Video: Connecting astrocytes to autism

by  /  13 October 2012

Star-shaped cells in the brain wrap themselves around synapses, the junctions between neurons, and influence their development. In a video interview Saturday at the 2012 Society for Neuroscience annual meeting in New Orleans, Ben Barres discusses the possible role of astrocytes in autism.

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Neuroscience in NOLA

by  /  12 October 2012

After nine long years, the Society for Neuroscience annual meeting is returning to New Orleans. And SFARI.org’s reporters are ready to deliver the best advances in autism research that emerge.

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Molecular mechanisms: Angelman region affects serotonin

by  /  12 October 2012

Mice that model Angelman syndrome or have a duplication of the 15q11-13 chromosomal region have aberrant brain levels of the chemical messenger serotonin, according to a study published 16 August in PLoS One.

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‘Spiny mice’ model risk of autism from maternal infection

by  /  10 October 2012

The so-called ‘spiny mouse’ species has a gestational period twice as long as that of typical laboratory mice. This makes them good models for studying the link between prenatal exposure and autism risk, according to a study published 29 August in Brain, Behavior and Immunity.

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Genetics: RNA improvisations altered in autism

by  /  9 October 2012

RNA editing, which creates multiple forms of a protein, is common among proteins involved in neuronal signaling, and may be abnormal in people with autism, according to a study published 7 August in Molecular Psychiatry.

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Allen Institute aims to mass-produce stem cells

by  /  5 October 2012

The nonprofit Allen Institute for Brain Science in Seattle plans to make neurons from stem cells derived from people with a number of different disorders. The resource, described 25 September at a conference in New York, will be available to all scientists.

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Researchers uncover new drug target for fragile X

by  /  4 October 2012

Deleting an enzyme that regulates protein synthesis reverses some of the molecular and behavioral deficits in a mouse model of fragile X syndrome, according to research published 2 October in Neuron.

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