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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

March 2013

Cognition and behavior: Attention early indicator of autism

by  /  8 March 2013

Infants who are later diagnosed with autism are less attentive to the presence of a person onscreen at 6 months of age than their typically developing peers are, according to a study published 14 January in Biological Psychiatry.

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Atlas maps ‘junk’ DNA that may regulate brain development

by  /  6 March 2013

Researchers have cataloged thousands of DNA regions that may act as enhancers — regulating gene expression from afar — in the developing mouse and human brains, according to a study published 14 February in Cell.

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Genetics: Head size heterogeneous in autism

by  /  6 March 2013

Children who have autism and large heads may belong to different clinical subsets based on the ratio between their head size and height, according to a study published in the February issue of Autism Research.

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What does the brain’s immunity have to do with autism?

by  /  4 March 2013

In December, SFARI brought together a group of scientists studying the connection between microglia and autism. These scientists are trying to delineate the next steps for this emerging field. Join the conversation.

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Test case

by ,  /  1 March 2013

A single case study suggests that deep brain stimulation may improve symptoms associated with autism, say Casey Halpern and Gregory Heuer.

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Molecular mechanisms: Deletion moves inhibitory neurons

by  /  1 March 2013

Loss of one copy of 22q11.2 — a chromosomal region linked to schizophrenia and autism — shifts the location of neurons that inhibit brain signals, according to a study published 6 November in Proceedings of the National Academy of Sciences.

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February 2013

Scientists follow brain activity as fish find their dinner

by  /  27 February 2013

Using a sensitive new imaging molecule, researchers can watch neurons in the larval zebrafish brain spring into action when the fish sees a potential meal, according to a study published 29 January in Current Biology.

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Illustration of a simulated view through binoculars.

Cognition and behavior: Visual perception enhanced in autism

by  /  27 February 2013

People with autism are adept at detecting whether two items appear on a screen simultaneously or close together in time, according to a study published 14 December in the Journal of Autism and Developmental Disorders.

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Risk factors

by ,  /  26 February 2013

To focus the search for environmental risk factors in autism, we should look for chemicals that influence the molecular pathways associated with candidate risk genes, say Pamela Lein and Marianna Stamou.

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Genetics: Double hit of risk genes recurrent in autism

by  /  26 February 2013

A boy with autism lacks one copy of SHANK2 and has a duplication of CHRNA7, two genes that have been linked together to autism risk, according to a case study published 25 January in Clinical Genetics.

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