Tag: UBE3A

August 2019
News

What matters for protein linked to autism? Location, location, location

by  /  14 August 2019

One form of the protein implicated in Angelman syndrome and autism clusters in the nucleus, and it’s this form that may be critical to brain development.

0 Comments
July 2019
News

Gene linked to multiple forms of autism may boost risk of death from seizures

by  /  18 July 2019

Mice with extra copies of UBE3A, a gene linked to autism and related conditions, are susceptible to death from seizures.

0 Comments
June 2019
children standing in a line, oldest to youngest
News

Timing of autism treatments may be key to their success

by  /  20 June 2019

The timing of treatment is crucial for conditions related to autism — and more so for some conditions than for others.

0 Comments
April 2019
Human fetus with molecules going into it's brain
News

Injecting CRISPR into fetal brain may correct autism mutations

by  /  24 April 2019

Researchers are edging closer to a therapy for Angelman syndrome — a condition related to autism — that involves injecting the gene-editing enzyme CRISPR into the fetal brain.

0 Comments
November 2018
News

Stem cells could deliver gene therapy for Angelman syndrome

by  /  7 November 2018

Modified stem cells show promise for delivering gene-based therapies to individuals with Angelman syndrome.

0 Comments
September 2018
Mouse brain slices glow green and blue in microscope view.
News

Cancer drug finds new use as treatment for Angelman syndrome

by  /  26 September 2018

Compounds that mimic a cancer drug restore expression of the key gene mutated in Angelman syndrome, a condition related to autism.

0 Comments
August 2018
Group of people in medical waiting room.
News

New diagnostic code for Angelman syndrome may spark crucial research

by  /  15 August 2018

The international manual of conditions now includes a diagnostic code for Angelman syndrome — which may enable scientists to systematically collect information about the syndrome.

0 Comments
December 2017
Week of DecemberDec
4th
2017
News / Spotted

Pruning protein; cultural connection; cannabis consent and more

by  /  8 December 2017

A pruning protein reshapes neurons, culture should be a consideration in trials of autism treatments, and another U.S. state adds autism to the list of indications for medical cannabis.

1 Comment
November 2017
Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.
News

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

0 Comments
July 2017
News

Anxiety, seizures mark mice with extra copy of autism gene

by  /  31 July 2017

Mice with an extra copy of UBE3A, a gene linked to autism, have learning problems and anxiety, and are prone to seizures and fine-motor problems.

0 Comments