Three articles published in the past few weeks show that diagnostic categories marked off neatly on the page often bleed together messily in the clinic.
Autism and intellectual disability often occur together, but in most cases that overlap is not genetic, according to a study of twin pairs published in the American Journal of Medical Genetics. Unraveling this link might help researchers pinpoint brain circuits involved in both conditions, and better understand the diversity of symptoms in the autism spectrum, experts say.
Attention deficit hyperactivity disorder (ADHD) and autism may have more in common than childhood onset and a few similar symptoms. New research suggests the conditions share genetic roots.
Random changes in gene expression can cause genetically identical embryos to develop different traits, according to a study of worms published in Nature. The findings suggest that haphazard movements of molecules could partly explain why autism-associated mutations don’t always cause the same symptoms.
The ability to recognize faces and interpret facial expressions is programmed partly by genes and inherited separately from other traits, according to three independent studies published this year.
A class of medications widely used during pregnancy to treat asthma and prevent early labor increases the baby’s risk of autism and other psychiatric disorders, according to a controversial review in the American Journal of Obstetrics and Gynecology.
Interested more in ideas than in dominating a crowded field, Michael Wigler decided to apply his expertise in cancer genetics to studying poorly understood features of autism.
In the fall of 1980, when he left his hometown of St. Louis, Missouri, for undergraduate studies at Cornell University in upstate New York, John Constantino was determined to pursue one of two careers: a doctor or a school teacher.
Autism is caused by poor parenting, particularly by ‘frigid’ mothers who reject their children. Such a statement would seem bizarre today. But 30 years ago parents, especially mothers, were blamed for their childrenʼs autism. But then in 1977, one study, published in the Journal of Child Psychology and Psychiatry, single-handedly turned the field around to recognize the importance of genetics.