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Spectrum: Autism Research News

Tag: sequencing

May 2015
Week of AprilApr
27th
2015

Spotted: Peer power; N of 1

by  /  1 May 2015

Peer review panels really can suss out good science, and clinical trials could get extremely personal.

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April 2015
Week of AprilApr
20th
2015

Spotted: Newt’s plea; CRISPR caution

by  /  24 April 2015

Newt Gingrich wants to double spending on medical research, and Chinese researchers highlight the hazards of editing human genomes.

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Iceland’s genomes offer glimpse into mutations’ varied effects

by  /  3 April 2015

Through a clever combination of sequencing genes and tracing family ties, Icelandic researchers have gathered genomic information for nearly one-third of their nation’s population.  

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March 2015

Women with severe autism point to new gene candidates

by  /  26 March 2015

Looking in families with a history of severe autism among women, researchers have unearthed 18 new candidate genes for the disorder. One of these genes, delta-catenin, plays a critical role in brain development, researchers reported yesterday in Nature.

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Magnetic beads map gene expression in single cells

by  /  25 March 2015

Newly developed microscopic beads give cells unique barcodes based on the cells’ gene expression patterns. This faster and cheaper system could help researchers study autism in cultured cells.

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Clever new method coaxes chromatin from living tissues

by  /  18 March 2015

A new method allows researchers to extract chromatin — the DNA-protein complex that helps to regulate gene expression — from tissue samples weighing as little as 1 milligram.

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February 2015
Week of FebruaryFeb
23rd
2015

Spotted: Social cells; brain bulge

by  /  27 February 2015

A cluster of neurons helps monkeys cooperate, and a human gene makes a mouse brain look like a person’s.

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Web of autism genes untangles slowly

by  /  20 February 2015

A new study maps the many targets of the autism gene TBR1, but it’s just one small piece of a much bigger picture.

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Some sibling sets arrive at autism with different mutations

by  /  5 February 2015

Less than one-third of sibling pairs with autism who carry rare mutations in autism-linked genes share those mutations, according to the largest study yet to sequence whole genomes of people with the disorder. The study questions the assumption that autism’s risk factors run in families, but some experts are skeptical.

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January 2015

Method charts lifetime expression of DNA in brain

by  /  21 January 2015

A new database that maps changes in gene expression in the prefrontal cortex shows that autism-linked genes are expressed differently than other genes through six stages of life.

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